Objective: To describe a patient with severe, recalcitrant mucous membrane erosions and chronic lymphocytic leukemia. Design: We present a case report and a literature review of paraneoplastic pemphigus. Material and Methods: Immunofluorescence studies and immunoprecipitation confirmed the presence of autoantibodies characteristic of paraneoplastic pemphigus in the patient's serum. Results: Our patient lived almost 8 years after the onset of paraneoplastic pemphigus, the longest time that anyone with this disease is known to have survived. Conclusion: The clinical course of paraneoplastic pemphigus tends to be rapid and fatal despite immunosuppressive therapy. Long-term survival is uncommon.
|Original language||English (US)|
|Number of pages||5|
|Journal||Mayo Clinic Proceedings|
|State||Published - 1994|
ASJC Scopus subject areas