Abstract
Autoimmune serological testing is a useful aid for identifying a paraneoplastic basis for sporadic motor neuron disease. A 67-year-old woman with ovarian carcinoma presented with progressive weakness. Neurological examination was suggestive of motor neuron disease with signs of upper motor neuron disorder. Electromyography revealed severe motor neuronopathy of the upper extremities. Characteristic type 1 Purkinje cell antibodies (anti-Yo antibody) was detected in the serum diluted at 1:61,400.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 943-945 |
| Number of pages | 3 |
| Journal | Muscle and Nerve |
| Volume | 21 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1998 |
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Keywords
- Anti-Yo
- Motor neuron disease
- Ovarian cancer
- Paraneoplastic
- Type 1 Purkinje cell antibodies
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Paraneoplastic motor neuron disease with type 1 Purkinje cell antibodies. / Khwaja, Shamsuddin; Sripathi, Naganand; Ahmad, B. K.; Lennon, Vanda A.
In: Muscle and Nerve, Vol. 21, No. 7, 07.1998, p. 943-945.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Paraneoplastic motor neuron disease with type 1 Purkinje cell antibodies
AU - Khwaja, Shamsuddin
AU - Sripathi, Naganand
AU - Ahmad, B. K.
AU - Lennon, Vanda A
PY - 1998/7
Y1 - 1998/7
N2 - Autoimmune serological testing is a useful aid for identifying a paraneoplastic basis for sporadic motor neuron disease. A 67-year-old woman with ovarian carcinoma presented with progressive weakness. Neurological examination was suggestive of motor neuron disease with signs of upper motor neuron disorder. Electromyography revealed severe motor neuronopathy of the upper extremities. Characteristic type 1 Purkinje cell antibodies (anti-Yo antibody) was detected in the serum diluted at 1:61,400.
AB - Autoimmune serological testing is a useful aid for identifying a paraneoplastic basis for sporadic motor neuron disease. A 67-year-old woman with ovarian carcinoma presented with progressive weakness. Neurological examination was suggestive of motor neuron disease with signs of upper motor neuron disorder. Electromyography revealed severe motor neuronopathy of the upper extremities. Characteristic type 1 Purkinje cell antibodies (anti-Yo antibody) was detected in the serum diluted at 1:61,400.
KW - Anti-Yo
KW - Motor neuron disease
KW - Ovarian cancer
KW - Paraneoplastic
KW - Type 1 Purkinje cell antibodies
UR - http://www.scopus.com/inward/record.url?scp=0031744417&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031744417&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-4598(199807)21:7<943::AID-MUS14>3.0.CO;2-R
DO - 10.1002/(SICI)1097-4598(199807)21:7<943::AID-MUS14>3.0.CO;2-R
M3 - Article
C2 - 9626256
AN - SCOPUS:0031744417
VL - 21
SP - 943
EP - 945
JO - Muscle and Nerve
JF - Muscle and Nerve
SN - 0148-639X
IS - 7
ER -