TY - JOUR
T1 - Parametric display of myocardial function
AU - Eusemann, Christian D.
AU - Ritman, Erik L.
AU - Bellemann, Matthias E.
AU - Robb, Richard A.
N1 - Funding Information:
Christian D. Eusemann received his Diplom Ingenieur Fachhochschule from the University of Applied Sciences of Jena, Germany in 1999. He is currently a Graduate Student working on his PhD in Biomedical Engineering at Mayo Graduate School. He was the recipient of a Carl Duisberg Society Research Fellowship Abroad for University of Applied Sciences Students in Germany and a Whitaker Foundation Student Travel Award for SPIE 2001 Image-Guided Procedures meeting. His research interest is in Cardiac Functional Imaging, and he has published four papers in this field.
Funding Information:
Matthias E. Bellemann studied Physics, Mathematics, and Computer Science at the University of Heidelberg, Germany. During his studies, he received a renowned scholarship from the German National Scholarship Foundation (Studienstiftung des deutschen Volkes). Having obtained his Diploma degree in Physics in 1989, he started his studies in Medicine at the Medical School of the University of Heidelberg. In 1992 he received his PhD degree in Biophysics jointly from the Max-Planck-Institute of Experimental Medicine and the University of Heidelberg. During his academic and professional education, Dr Bellemann joined the Max-Planck Institute of Nuclear Physics in Heidelberg, the European Molecular Biology Laboratory in Hamburg, and the German Cancer Research Center in Heidelberg. In 1997 he was appointed as a full Professor of Medical Physics at the University of Applied Sciences, Jena, Germany. He is currently Associate Dean for Research Affairs at the Department of Biomedical Engineering at the University of Applied Sciences. His research interests are focused on the development and application of advanced imaging techniques for quantitative mapping of functional biomedical data. He is a member of the International Society for Magnetic Resonance in Medicine, the German Roentgen Society, the German Society for Nuclear Medicine, and the German Society for Medical Physics. He is reviewer of several prestigious national and international journals. He has been and is principal investigator on several national research grants. He has authored or co-authored over 40 peer-reviewed journal articles in the field of biomedical imaging. Dr Bellemann's research interests are in functional biomedical imaging techniques (MRI, PET, CT, and US), image analysis (registration, parameter mapping), signal processing (biostatistics, pharmacokinetic modeling), and application of these procedures in experimental and clinical trials. He has developed several specific clinical applications of these techniques, including carbon-13 MR spectroscopy for tumor characterization and monitoring, pharmacokinetic modeling of PET data for follow-up studies during therapy, 3D image registration in MR mammography, and electromagnetic field calculation for image-guided transcranial magnetic stimulation. His research interests also include the development and evaluation of new inter-modality imaging techniques as well as the combined application of diagnostic and therapeutic procedures.
PY - 2001
Y1 - 2001
N2 - Quantitative assessment of regional heart motion has significant potential to provide more specific diagnosis of cardiac disease and cardiac malfunction than currently possible. Local heart motion may be captured from various medical imaging scanners. In this study, 3-D reconstructions of pre-infarct and post-infarct hearts were obtained from the Dynamic Spatial Reconstructor [Ritman EL, Robb RA, Harris LD. Imaging physiological functions: experience with the DSR. Philadelphia: Praeger, 1985; Robb RA, Lent AH, Gilbert BK, Chu A. The dynamic spatial reconstructor: a computed tomography system for high-speed simultaneous scanning of multiple cross sections of the heart. J Med Syst 1980;4(2):253-88; Jorgensen SM, Whitlock SV, Thomas PJ, Roessler RW, Ritman EL. The dynamic spatial reconstructor: a high speed, stop action, 3-D, digital radiographic imager of moving internal organs and blood. Proceedings of SPIE, Ultrahigh- and High-speed Photography, Videography, Photonics, and Velocimetry 1990;1346:180-91.] (DSR). Using functional parametric mapping of disturbances in regional contractility and relaxation, regional myocardial motion during a cardiac cycle is color mapped onto a deformable heart model to facilitate appreciation of the structure-to-function relationships in the myocardium, such as occurs in regional patterns of akinesis or dyskinesis associated with myocardial ischemia or infarction resulting from coronary artery occlusion.
AB - Quantitative assessment of regional heart motion has significant potential to provide more specific diagnosis of cardiac disease and cardiac malfunction than currently possible. Local heart motion may be captured from various medical imaging scanners. In this study, 3-D reconstructions of pre-infarct and post-infarct hearts were obtained from the Dynamic Spatial Reconstructor [Ritman EL, Robb RA, Harris LD. Imaging physiological functions: experience with the DSR. Philadelphia: Praeger, 1985; Robb RA, Lent AH, Gilbert BK, Chu A. The dynamic spatial reconstructor: a computed tomography system for high-speed simultaneous scanning of multiple cross sections of the heart. J Med Syst 1980;4(2):253-88; Jorgensen SM, Whitlock SV, Thomas PJ, Roessler RW, Ritman EL. The dynamic spatial reconstructor: a high speed, stop action, 3-D, digital radiographic imager of moving internal organs and blood. Proceedings of SPIE, Ultrahigh- and High-speed Photography, Videography, Photonics, and Velocimetry 1990;1346:180-91.] (DSR). Using functional parametric mapping of disturbances in regional contractility and relaxation, regional myocardial motion during a cardiac cycle is color mapped onto a deformable heart model to facilitate appreciation of the structure-to-function relationships in the myocardium, such as occurs in regional patterns of akinesis or dyskinesis associated with myocardial ischemia or infarction resulting from coronary artery occlusion.
KW - Functional mapping
KW - Heart motion analysis
KW - Myocardial dynamics
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U2 - 10.1016/S0895-6111(01)00009-X
DO - 10.1016/S0895-6111(01)00009-X
M3 - Article
C2 - 11679210
AN - SCOPUS:0034778709
VL - 25
SP - 483
EP - 493
JO - Computerized Medical Imaging and Graphics
JF - Computerized Medical Imaging and Graphics
SN - 0895-6111
IS - 6
ER -