Parameters affecting microinjections of adenosine into the brainstem of rats

R. A. Barraco, Petra Marcela Casey, C. J. Janusz

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

It is well established that the Nucleus Tractus Solitarius (NTS) is the major relay nucleus for afferent input from baroreceptors and thereby plays a critical role in central cardiovascular control. A variety of neuroactive substances elicit potent cardiovascular responses following microinjection into the NTS. Since the issue of localization is very important in these studies, the aim of the present study was to examine the technical parameters of administering adenosine, a putative neuromodulator, via microinjection into the NTS. The results show that injection parameters are consequential and that adenosine elicits potent cardiovascular responses following microinjection into the NTS.

Original languageEnglish (US)
Pages (from-to)797-799
Number of pages3
JournalMedical Science Research
Volume15
Issue number13
StatePublished - 1987
Externally publishedYes

Fingerprint

Solitary Nucleus
Microinjections
Adenosine
Brain Stem
Rats
Neurotransmitter Agents
Pressoreceptors
Injections

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Parameters affecting microinjections of adenosine into the brainstem of rats. / Barraco, R. A.; Casey, Petra Marcela; Janusz, C. J.

In: Medical Science Research, Vol. 15, No. 13, 1987, p. 797-799.

Research output: Contribution to journalArticle

@article{c43f0946d01f4f429e6029953f0d6257,
title = "Parameters affecting microinjections of adenosine into the brainstem of rats",
abstract = "It is well established that the Nucleus Tractus Solitarius (NTS) is the major relay nucleus for afferent input from baroreceptors and thereby plays a critical role in central cardiovascular control. A variety of neuroactive substances elicit potent cardiovascular responses following microinjection into the NTS. Since the issue of localization is very important in these studies, the aim of the present study was to examine the technical parameters of administering adenosine, a putative neuromodulator, via microinjection into the NTS. The results show that injection parameters are consequential and that adenosine elicits potent cardiovascular responses following microinjection into the NTS.",
author = "Barraco, {R. A.} and Casey, {Petra Marcela} and Janusz, {C. J.}",
year = "1987",
language = "English (US)",
volume = "15",
pages = "797--799",
journal = "Medical Science Research",
issn = "0269-8951",
publisher = "Lippincott Williams and Wilkins",
number = "13",

}

TY - JOUR

T1 - Parameters affecting microinjections of adenosine into the brainstem of rats

AU - Barraco, R. A.

AU - Casey, Petra Marcela

AU - Janusz, C. J.

PY - 1987

Y1 - 1987

N2 - It is well established that the Nucleus Tractus Solitarius (NTS) is the major relay nucleus for afferent input from baroreceptors and thereby plays a critical role in central cardiovascular control. A variety of neuroactive substances elicit potent cardiovascular responses following microinjection into the NTS. Since the issue of localization is very important in these studies, the aim of the present study was to examine the technical parameters of administering adenosine, a putative neuromodulator, via microinjection into the NTS. The results show that injection parameters are consequential and that adenosine elicits potent cardiovascular responses following microinjection into the NTS.

AB - It is well established that the Nucleus Tractus Solitarius (NTS) is the major relay nucleus for afferent input from baroreceptors and thereby plays a critical role in central cardiovascular control. A variety of neuroactive substances elicit potent cardiovascular responses following microinjection into the NTS. Since the issue of localization is very important in these studies, the aim of the present study was to examine the technical parameters of administering adenosine, a putative neuromodulator, via microinjection into the NTS. The results show that injection parameters are consequential and that adenosine elicits potent cardiovascular responses following microinjection into the NTS.

UR - http://www.scopus.com/inward/record.url?scp=0023213250&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023213250&partnerID=8YFLogxK

M3 - Article

VL - 15

SP - 797

EP - 799

JO - Medical Science Research

JF - Medical Science Research

SN - 0269-8951

IS - 13

ER -