Pancreatic cancer microenvironment, to target or not to target?

Research output: Contribution to journalComment/debate

23 Scopus citations

Abstract

We have collectively been spoiled by the astounding clinical benefit of antimicrobials. Much like the discovery and use of penicillin to eradicate once deadly infections, we continue to desperately search for the next "magic bullet" to kill cancer while sparing the non-transformed cells. Greater appreciation for the molecular intricacies of malignancy has resulted in dedicated pursuit of cancer genomics and large-scale informatics to identify "drugable" targets within the cancer cell itself. However, studies at the bench elucidating a dynamic relationship between tumor and microenvironment have become more common and demonstrate promise for novel therapeutic intervention.

Original languageEnglish (US)
Pages (from-to)80-82
Number of pages3
JournalEMBO Molecular Medicine
Volume8
Issue number2
DOIs
StatePublished - Feb 1 2016

ASJC Scopus subject areas

  • Molecular Medicine

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