TY - JOUR
T1 - Pain, neuropathic symptoms, and physical and mental well-being in persons with cancer
AU - Tofthagen, Cindy
AU - McMillan, Susan C.
PY - 2010/11
Y1 - 2010/11
N2 - Background: Neuropathic pain is present in at least 25% to 40% of people with cancer pain and is thought to be more difficult to control than other types of cancer-related pain. Objective: The purpose of this study was to explore differences in the experience of cancer patients who describe their pain using neuropathic descriptors compared with those who do not. Methods: A secondary analysis of data from 234 outpatients from a large National Cancer Institute-designated cancer center in west central Florida was conducted to identify differences in pain, pain interference, symptoms, health-related quality of life, and depression between the 2 groups. Results: Patients with numbness, tingling, or electric-like sensations reported higher levels of current pain (P =.001), pain at its worst (P =.001), pain on average (P =.019), pain at its least (P =.008), and pain interference (P <.001). They reported problems with dizziness/lightheadedness significantly more often (P =.004) and also reported more severe problems with concentration (P =.047) and poorer physical (P =.019) and mental health (P =.024), although no differences in depressive symptoms were found. Conclusions: The results of this study indicate that cancer patients with numbness, tingling, or electric-like sensations have significantly higher levels of pain and pain interference and lower health-related quality of life than do patients without these symptoms. Implications For Practice: These results highlight the ongoing need for research evaluating methods of treating neuropathic pain, education regarding assessment and management of neuropathic pain, and aggressive efforts to relieve neuropathic pain in oncology settings.
AB - Background: Neuropathic pain is present in at least 25% to 40% of people with cancer pain and is thought to be more difficult to control than other types of cancer-related pain. Objective: The purpose of this study was to explore differences in the experience of cancer patients who describe their pain using neuropathic descriptors compared with those who do not. Methods: A secondary analysis of data from 234 outpatients from a large National Cancer Institute-designated cancer center in west central Florida was conducted to identify differences in pain, pain interference, symptoms, health-related quality of life, and depression between the 2 groups. Results: Patients with numbness, tingling, or electric-like sensations reported higher levels of current pain (P =.001), pain at its worst (P =.001), pain on average (P =.019), pain at its least (P =.008), and pain interference (P <.001). They reported problems with dizziness/lightheadedness significantly more often (P =.004) and also reported more severe problems with concentration (P =.047) and poorer physical (P =.019) and mental health (P =.024), although no differences in depressive symptoms were found. Conclusions: The results of this study indicate that cancer patients with numbness, tingling, or electric-like sensations have significantly higher levels of pain and pain interference and lower health-related quality of life than do patients without these symptoms. Implications For Practice: These results highlight the ongoing need for research evaluating methods of treating neuropathic pain, education regarding assessment and management of neuropathic pain, and aggressive efforts to relieve neuropathic pain in oncology settings.
KW - Neuropathy
KW - Pain
KW - Performance
KW - Quality of life
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U2 - 10.1097/NCC.0b013e3181e212b4
DO - 10.1097/NCC.0b013e3181e212b4
M3 - Article
C2 - 21479139
AN - SCOPUS:78049490607
SN - 0162-220X
VL - 33
SP - 436
EP - 444
JO - Cancer Nursing
JF - Cancer Nursing
IS - 6
ER -