Paclitaxel-Induced delayed hypersensivity pneumonitis complicating lymphangitic spread of ovarian carcinoma

W. Jackson, Alexander Niven, W. Winter, A. Shorr

Research output: Contribution to journalArticle


The differential diagnosis of subacute respiratory failure in the immunosuppressed cancer patient is extensive, and includes primarily infectious, thromboembolic and cardiac disorders. Chemotherapeutic drug reactions and progression of underlying malignancy must be readily considered in this population as well. We describe a case of delayed hypersensitivity pneumonitis requiring mechanical ventilation secondary to paclitaxel in a patient with coexistent intrathoracic spread of ovarian cancer, a previously unreported entity. Treatment with corticosteroids resulted in marked clinical and radiographic improvement.

Original languageEnglish (US)
Pages (from-to)131-134
Number of pages4
JournalClinical Intensive Care
Issue number2-3
StatePublished - Sep 1 2002
Externally publishedYes


ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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