Pacemaker induced mitral regurgitation: An alternative form of pacemaker syndrome

Charles R. Cannan, Stuart T. Higano, David R. Holmes

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


A patient in atrial fibrillation was referred for mitral valve replacement due to severe mitral regurgitation. A cardiac pacemaker had previously been implanted. Cardiac catheterization demonstrated large V waves in the wedge pressure tracing during ventricular pacing, which were not present during native conduction. A left ventriculogram demonstrated severe mitral regurgitation during ventricular pacing, but not during native conduction. This patient, in atrial fibrillation, had severe mitral regurgitation induced by ventricular pacing and not by native conduction. Pacemaker syndrome may be caused by mitral regurgitation that is probably not secondary to AV dissociation, but rather the result of dyssynchronous ventricular contraction.

Original languageEnglish (US)
Pages (from-to)735-738
Number of pages4
JournalPACE - Pacing and Clinical Electrophysiology
Issue number3 I
StatePublished - Apr 5 1997


  • atrial fibrillation
  • mitral regurgitation
  • pacemaker syndrome
  • ventricular pacing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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