Oxymorphone: A review

Eric Prommer

Research output: Contribution to journalReview article

55 Scopus citations


Oxymorphone (oxymorphone hydrochloride) (14-hydroxydihydromorphinone), a semisynthetic μ-opioid agonist, was first approved by the US Food and Drug Administration in 1959. Oxymorphone is considered a more potent opioid than its parent compound, morphine. Recently, an immediate-release and long-acting oral formulation of this drug was developed that makes oxymorphone a new option in treating moderate to severe pain. This article reviews the pharmacodynamics, pharmacology, and clinical efficacy for this new option in treating moderate to severe pain.

Original languageEnglish (US)
Pages (from-to)109-115
Number of pages7
JournalSupportive Care in Cancer
Issue number2
StatePublished - Feb 1 2006



  • Opioid
  • Opioid receptors
  • Oxymorphone
  • Pharmacokinetics

ASJC Scopus subject areas

  • Oncology

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