Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding ras and activating ras signaling

Agriculture & Biology

• pancreatic neoplasms 100%
• galectins 89%
• neoplasm cells 56%
• cell proliferation 55%
• neoplasm progression 15%
• neoplasms 11%
• animal models 9%
• Lentivirus 7%
• mutation 7%
• galactosides 6%
• protein-protein interactions 5%
• transfection 5%
• immunohistochemistry 5%
• lethal genes 5%
• fluorescent antibody technique 4%
• phosphorylation 4%
• binding proteins 4%
• cell lines 3%
• mutants 3%
• assays 2%
• cells 1%

Medicine & Life Sciences

• Galectin 3 81%
• Pancreatic Neoplasms 58%
• Cell Proliferation 40%
• Galactosides 8%
• Down-Regulation 7%
• Lentivirus 6%
• Mutation 5%
• Immunoprecipitation 5%
• Tumor Burden 4%
• Transfection 4%
• Fluorescent Antibody Technique 4%
• Carrier Proteins 4%
• Small Interfering RNA 4%
• Complementary DNA 4%
• Proteins 3%
• Immunohistochemistry 3%
• Phosphorylation 3%
• Neoplasms 3%
• Cell Line 3%
• Polymerase Chain Reaction 3%
• Survival 2%
• In Vitro Techniques 2%

Chemical Compounds

• Mutation 52%
• Small Interfering RNA 42%
• Lethal 36%
• Complementary DNA 32%
• Volume 17%
• Protein 12%