TY - JOUR
T1 - Overcoming antibody barriers to transplantation
T2 - ABO-incompatible and positive cross-match kidney transplantation at Mayo Clinic - Rochester
AU - Stegall, Mark D.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2006/7
Y1 - 2006/7
N2 - Over the past several years, protocols have been developed to allow patients with antibody against either donor blood group (ABO-incompatible) or donor HLA antigens (positive cross-match) to undergo successful kidney transplantation. Important factors determining the development of hyperacute rejection, humoral rejection and long-term graft survival have been defined. In this review, the clinical experience with ABO-incompatible and positive cross-match kidney transplantation at Mayo Clinic, Rochester are described with an emphasis on both patient management issues and gaps in our current knowledge in this emerging field.
AB - Over the past several years, protocols have been developed to allow patients with antibody against either donor blood group (ABO-incompatible) or donor HLA antigens (positive cross-match) to undergo successful kidney transplantation. Important factors determining the development of hyperacute rejection, humoral rejection and long-term graft survival have been defined. In this review, the clinical experience with ABO-incompatible and positive cross-match kidney transplantation at Mayo Clinic, Rochester are described with an emphasis on both patient management issues and gaps in our current knowledge in this emerging field.
KW - DSA
KW - Donor-specific alloantibody
KW - Living donor kidney transplantation (LDKTx)
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U2 - 10.1016/j.ics.2006.03.057
DO - 10.1016/j.ics.2006.03.057
M3 - Article
AN - SCOPUS:33748927652
SN - 0531-5131
VL - 1292
SP - 113
EP - 119
JO - International Congress Series
JF - International Congress Series
ER -