Ovarian leiomyoma with hilus cell hyperplasia that caused virilization

J. M. Parish, E. G. Lufkin, R. A. Lee, T. A. Gaffey

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalMayo Clinic Proceedings
Volume59
Issue number4
StatePublished - 1984

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Virilism
Leiomyoma
Hyperplasia
Testosterone
Ketosteroids
Laparotomy
Ovary
Steroids
Cell Proliferation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Parish, J. M., Lufkin, E. G., Lee, R. A., & Gaffey, T. A. (1984). Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. Mayo Clinic Proceedings, 59(4), 275-277.

Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. / Parish, J. M.; Lufkin, E. G.; Lee, R. A.; Gaffey, T. A.

In: Mayo Clinic Proceedings, Vol. 59, No. 4, 1984, p. 275-277.

Research output: Contribution to journalArticle

Parish, JM, Lufkin, EG, Lee, RA & Gaffey, TA 1984, 'Ovarian leiomyoma with hilus cell hyperplasia that caused virilization', Mayo Clinic Proceedings, vol. 59, no. 4, pp. 275-277.
Parish JM, Lufkin EG, Lee RA, Gaffey TA. Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. Mayo Clinic Proceedings. 1984;59(4):275-277.
Parish, J. M. ; Lufkin, E. G. ; Lee, R. A. ; Gaffey, T. A. / Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. In: Mayo Clinic Proceedings. 1984 ; Vol. 59, No. 4. pp. 275-277.
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