Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization

JAMES M. PARISH; EDWARD G. LUFKIN; RAYMOND A. LEE; THOMAS A. GAFFEY

doi:10.1016/S0025-6196(12)61262-2

Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization

JAMES M. PARISH, EDWARD G. LUFKIN, RAYMOND A. LEE, THOMAS A. GAFFEY

Pulmonary Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.

Original language	English (US)
Pages (from-to)	275-277
Number of pages	3
Journal	Mayo Clinic proceedings
Volume	59
Issue number	4
DOIs	https://doi.org/10.1016/S0025-6196(12)61262-2
State	Published - 1984

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/S0025-6196(12)61262-2

Cite this

@article{4589891de7bb4444885cd5ad858d76ef,

title = "Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization",

abstract = "A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.",

author = "PARISH, {JAMES M.} and LUFKIN, {EDWARD G.} and LEE, {RAYMOND A.} and GAFFEY, {THOMAS A.}",

year = "1984",

doi = "10.1016/S0025-6196(12)61262-2",

language = "English (US)",

volume = "59",

pages = "275--277",

journal = "Mayo Clinic proceedings",

issn = "0025-6196",

publisher = "Elsevier Science",

number = "4",

}

TY - JOUR

T1 - Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization

AU - PARISH, JAMES M.

AU - LUFKIN, EDWARD G.

AU - LEE, RAYMOND A.

AU - GAFFEY, THOMAS A.

PY - 1984

Y1 - 1984

N2 - A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.

AB - A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.

UR - http://www.scopus.com/inward/record.url?scp=0021321096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021321096&partnerID=8YFLogxK

U2 - 10.1016/S0025-6196(12)61262-2

DO - 10.1016/S0025-6196(12)61262-2

M3 - Article

C2 - 6708605

AN - SCOPUS:0021321096

SN - 0025-6196

VL - 59

SP - 275

EP - 277

JO - Mayo Clinic proceedings

JF - Mayo Clinic proceedings

IS - 4

ER -

Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this