Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization

JAMES M. PARISH, EDWARD G. LUFKIN, RAYMOND A. LEE, THOMAS A. GAFFEY

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

A 68-year-old woman had noted gradual virilization and depression for 3 years. Examination revealed a 10-cm right pelvic mass. Plasma testosterone was substantially elevated (1,082 ng/dl), but urinary ketosteroid and ketogenic steroid excretion was normal. Laparotomy revealed a 10-cm mass that replaced the right ovary and weighed 210 g. Histologic analysis revealed a leiomyoma and proliferation of hilus cells in the periphery of the mass. The plasma testosterone decreased postoperatively to 45 ng/dl. We believe that this is the first report of an ovarian leiomyoma associated with hilus cell hyperplasia that caused virilization.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalMayo Clinic proceedings
Volume59
Issue number4
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization'. Together they form a unique fingerprint.

  • Cite this

    PARISH, JAMES. M., LUFKIN, EDWARD. G., LEE, RAYMOND. A., & GAFFEY, THOMAS. A. (1984). Ovarian Leiomyoma With Hilus Cell Hyperplasia That Caused Virilization. Mayo Clinic proceedings, 59(4), 275-277. https://doi.org/10.1016/S0025-6196(12)61262-2