Outcome of penicillin-susceptible streptococcal prosthetic joint infection treated with debridement and retention of the prosthesis

A. M. Meehan, Douglas R. Osmon, M. C T Ouffy, A. D. Hanssen, M. R. Keating

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110 Citations (Scopus)

Abstract

Debridement with retention of the prosthesis was the initial treatment modality for 19 cases of penicillin-susceptible streptococcal prosthetic joint infection that occurred in 18 patients who presented to the Mayo Clinic (Rochester, Minnesota) during 1969-1998. All of the cases of prosthetic joint infection occurred >30 days after implantation of the prosthesis, which was well fixed at the time of debridement. The median duration of symptoms before debridement was 4 days (range, 1-10 days). Treatment failure (defined as relapse of infection with the original microorganism) occurred in 2 cases (10.5%) during a median follow-up period of 3.9 years (range, 0.3-21.7 years). The 1-year cumulative risk of relapse was 11% (95% confidence interval, 0%-26%). Relapse of prosthetic joint infection due to penicillin-susceptible streptococci after debridement and retention of the prosthesis is uncommon. For patients who present with a well-fixed prosthesis and a short duration of symptoms, debridement with retention appears to be an effective treatment modality.

Original languageEnglish (US)
Pages (from-to)845-849
Number of pages5
JournalClinical Infectious Diseases
Volume36
Issue number7
DOIs
StatePublished - Apr 1 2003

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Prosthesis Retention
Debridement
Penicillins
Joints
Infection
Recurrence
Prosthesis Implantation
Streptococcus
Treatment Failure
Prostheses and Implants
Confidence Intervals
Therapeutics

ASJC Scopus subject areas

  • Immunology

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Outcome of penicillin-susceptible streptococcal prosthetic joint infection treated with debridement and retention of the prosthesis. / Meehan, A. M.; Osmon, Douglas R.; Ouffy, M. C T; Hanssen, A. D.; Keating, M. R.

In: Clinical Infectious Diseases, Vol. 36, No. 7, 01.04.2003, p. 845-849.

Research output: Contribution to journalArticle

Meehan, A. M. ; Osmon, Douglas R. ; Ouffy, M. C T ; Hanssen, A. D. ; Keating, M. R. / Outcome of penicillin-susceptible streptococcal prosthetic joint infection treated with debridement and retention of the prosthesis. In: Clinical Infectious Diseases. 2003 ; Vol. 36, No. 7. pp. 845-849.
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