Outcome of Adverse Events and Medical Errors in the Intensive Care Unit: A Systematic Review and Meta-analysis

Adil H. Ahmed, Jyothsna Giri, Rahul Kashyap, Balwinder Singh, Yue Dong, Oguz Kilickaya, Patricia J. Erwin, M. Hassan Murad, Brian W. Pickering

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Adverse events and medical errors (AEs/MEs) are more likely to occur in the intensive care unit (ICU). Information about the incidence and outcomes of such events is conflicting. A systematic review and meta-analysis were conducted to examine the effects of MEs/AEs on mortality and hospital and ICU lengths of stay among ICU patients. Potentially eligible studies were identified from 4 major databases. Of 902 studies screened, 12 met the inclusion criteria, 10 of which are included in the quantitative analysis. Patients with 1 or more MEs/AEs (vs no MEs/AEs) had a nonsignificant increase in mortality (odds ratio = 1.5; 95% confidence interval [CI] = 0.98-2.14) but significantly longer hospital and ICU stays; the mean difference (95% CI) was 8.9 (3.3-14.7) days for hospital stay and 6.8 (0.2-13.4) days for ICU. The ICU environment is associated with a substantial incidence of MEs/AEs, and patients with MEs/AEs have worse outcomes than those with no MEs/AEs.

Original languageEnglish (US)
Pages (from-to)23-30
Number of pages8
JournalAmerican Journal of Medical Quality
Volume30
Issue number1
DOIs
StatePublished - Jan 21 2015

Keywords

  • adverse events
  • intensive care unit
  • medical error
  • outcomes
  • systematic review

ASJC Scopus subject areas

  • Health Policy

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