Outcome in juvenile dermatomyositis

Vaidehi Chowdhary, Anupam Wakhlu, Amita Agarwal, Ramnath Misra

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The clinical features, outcome and complications of juvenile dermatomyositis were studied in a tertiary care hospital by retrospective analysis of case records. Nineteen patients were treated over an 11-year period. Median age at diagnosis was 12 years (2.5-16 years). Median duration of disease prior to diagnosis was 12 months (2-96 months). Proximal muscle weakness was seen in all 19 cases, neck muscle weakness in 14, pharyngeal muscle involvement in 5 and respiratory muscle involvement in 3 cases. Heliotrope rash was seen in 9 and Gottrons rash in 8 patients. Myocarditis and GI bleed were seen in I each while interstitial lung disease was seen in 2 patients. All except one patient received prednisolone. Methotrexate was used in 13 and azathioprine in 3 patients. Eight patients are in complete remission (CR), 8 partial remission and 2 patients had no response. Complications were calcinosis in 5, contractures in 2, TB in 4 and pyogenic infections in 4 patients. Juvenile dermatomyositis needs to be recognised early and treated aggressively to improve outcome.

Original languageEnglish (US)
Pages (from-to)931-935
Number of pages5
JournalIndian Pediatrics
Volume39
Issue number10
StatePublished - Oct 1 2002
Externally publishedYes

Fingerprint

Muscle Weakness
Exanthema
Pharyngeal Muscles
Neck Muscles
Calcinosis
Respiratory Muscles
Juvenile dermatomyositis
Interstitial Lung Diseases
Myocarditis
Azathioprine
Contracture
Tertiary Healthcare
Prednisolone
Tertiary Care Centers
Methotrexate
Infection
funiferine N-oxide

Keywords

  • Calcinosis
  • Connective tissue disease
  • Inflammatory myositis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Chowdhary, V., Wakhlu, A., Agarwal, A., & Misra, R. (2002). Outcome in juvenile dermatomyositis. Indian Pediatrics, 39(10), 931-935.

Outcome in juvenile dermatomyositis. / Chowdhary, Vaidehi; Wakhlu, Anupam; Agarwal, Amita; Misra, Ramnath.

In: Indian Pediatrics, Vol. 39, No. 10, 01.10.2002, p. 931-935.

Research output: Contribution to journalArticle

Chowdhary, V, Wakhlu, A, Agarwal, A & Misra, R 2002, 'Outcome in juvenile dermatomyositis', Indian Pediatrics, vol. 39, no. 10, pp. 931-935.
Chowdhary V, Wakhlu A, Agarwal A, Misra R. Outcome in juvenile dermatomyositis. Indian Pediatrics. 2002 Oct 1;39(10):931-935.
Chowdhary, Vaidehi ; Wakhlu, Anupam ; Agarwal, Amita ; Misra, Ramnath. / Outcome in juvenile dermatomyositis. In: Indian Pediatrics. 2002 ; Vol. 39, No. 10. pp. 931-935.
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