Osteosarcoma - an evaluation of current diagnosis, treatment and chemotherapy

Bahtiyar Demiralp, Gobinda Sarkar, Scott H. Okuno, Michael J. Yaszemski, Avudaiappan Maran

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Osteosarcoma is a bone tumour that most often affects children and young adults. Although a combination of surgery to remove the primary tumour and chemotherapy prior to and after the surgery has led to an improved survival rate, local recurrence and metastases still develop in two-fifths of patients. A definitive therapy is yet to be determined for this deadly disease. This article discusses the current status on diagnosis and treatment, with an emphasis on developing new molecularly targeted therapies.

Original languageEnglish (US)
Pages (from-to)18-23
Number of pages6
JournalEuropean Musculoskeletal Review
Volume6
Issue number1
StatePublished - Feb 1 2011

Keywords

  • 2-methoxyestradiol
  • Bone tumour
  • Chemotherapy
  • Osteosarcoma
  • Sarcoma
  • Tumour surgery

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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