Osteosarcoma

Bree R. Eaton; Rudolf Schwarz; Ralph Vatner; Brian Yeh; Line Claude; Daniel J. Indelicato; Nadia Laack

doi:10.1002/pbc.28352

Osteosarcoma

Bree R. Eaton, Rudolf Schwarz, Ralph Vatner, Brian Yeh, Line Claude, Daniel J. Indelicato, Nadia Laack

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.

Original language	English (US)
Article number	e28352
Journal	Pediatric Blood and Cancer
Volume	68
Issue number	S2
DOIs	https://doi.org/10.1002/pbc.28352
State	Published - May 2021

Keywords

chemotherapy
metastasis
osteosarcoma
radiotherapy
surgery

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1002/pbc.28352

Cite this

@article{de37da8dce2a4140bcec758eede0771c,

title = "Osteosarcoma",

abstract = "Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.",

keywords = "chemotherapy, metastasis, osteosarcoma, radiotherapy, surgery",

author = "Eaton, {Bree R.} and Rudolf Schwarz and Ralph Vatner and Brian Yeh and Line Claude and Indelicato, {Daniel J.} and Nadia Laack",

note = "Publisher Copyright: {\textcopyright} 2020 Wiley Periodicals LLC",

year = "2021",

month = may,

doi = "10.1002/pbc.28352",

language = "English (US)",

volume = "68",

journal = "Medical and Pediatric Oncology",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "S2",

}

TY - JOUR

T1 - Osteosarcoma

AU - Eaton, Bree R.

AU - Schwarz, Rudolf

AU - Vatner, Ralph

AU - Yeh, Brian

AU - Claude, Line

AU - Indelicato, Daniel J.

AU - Laack, Nadia

PY - 2021/5

Y1 - 2021/5

N2 - Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.

AB - Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.

KW - chemotherapy

KW - metastasis

KW - osteosarcoma

KW - radiotherapy

KW - surgery

UR - http://www.scopus.com/inward/record.url?scp=85089250075&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85089250075&partnerID=8YFLogxK

U2 - 10.1002/pbc.28352

DO - 10.1002/pbc.28352

M3 - Article

C2 - 32779875

AN - SCOPUS:85089250075

SN - 1545-5009

VL - 68

JO - Medical and Pediatric Oncology

JF - Medical and Pediatric Oncology

IS - S2

M1 - e28352

ER -

Osteosarcoma

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this