Orthostatic hypotension as a prodromal marker of α-synucleinopathies-Reply

Rodolfo Savica; Bradley F. Boeve; Michelle M. Mielke

doi:10.1001/jamaneurol.2018.2251

Orthostatic hypotension as a prodromal marker of α-synucleinopathies-Reply

Rodolfo Savica, Bradley F. Boeve, Michelle M. Mielke

Research output: Contribution to journal › Letter › peer-review

Original language	English (US)
Pages (from-to)	1155
Number of pages	1
Journal	JAMA neurology
Volume	75
Issue number	9
DOIs	https://doi.org/10.1001/jamaneurol.2018.2251
State	Published - Sep 2018

ASJC Scopus subject areas

Clinical Neurology

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10.1001/jamaneurol.2018.2251

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@article{971b316700674eebab7f1f27a57a02e5,

title = "Orthostatic hypotension as a prodromal marker of α-synucleinopathies-Reply",

author = "Rodolfo Savica and Boeve, {Bradley F.} and Mielke, {Michelle M.}",

note = "Funding Information: Author Affiliations: Department of Neurology, Dysautonomia Center, New York University School of Medicine, New York. Corresponding Author: Horacio Kaufmann, MD, Department of Neurology, Dysautonomia Center, New York University School of Medicine, 530 First Ave, Ste 9Q, New York, NY 10016 (horacio.kaufmann@nyumc.org). Published Online: August 13, 2018. doi:10.1001/jamaneurol.2018.2248 Conflict of Interest Disclosures: The authors receive funding from National Institutes of Health grant U54NS065736. 1. Savica R, Boeve BF, Mielke MM. When do α-synucleinopathies start? an epidemiological timeline: a review. JAMA Neurol. 2018;75(4):503-509. doi:10.1001/jamaneurol.2017.4243 2. Kaufmann H, Norcliffe-Kaufmann L, Palma JA, et al; Autonomic Disorders Consortium. Natural history of pure autonomic failure: a United States prospective cohort. Ann Neurol. 2017;81(2):287-297. doi:10.1002/ana.24877 3. Postuma RB, Gagnon JF, Pelletier A, Montplaisir J. Prodromal autonomic symptoms and signs in Parkinson{\textquoteright}s disease and dementia with Lewy bodies. Mov Disord. 2013;28(5):597-604. doi:10.1002/mds.25445 4. Schrag A, Horsfall L, Walters K, Noyce A, Petersen I. Prediagnostic presentations of Parkinson{\textquoteright}s disease in primary care: a case-control study. Lancet Neurol. 2015;14(1):57-64. doi:10.1016/S1474-4422(14)70287-X 5. Berg D, Postuma RB, Adler CH, et al. MDS research criteria for prodromal Parkinson{\textquoteright}s disease. Mov Disord. 2015;30(12):1600-1611. doi:10.1002/mds.26431 Funding Information: Conflict of Interest Disclosures: Our research is supported by grants from Funda{\c c}{\~a}o de Amparo {\`a} Pesquisa do Estado de S{\~a}o Paulo, Conselho Nacional de Desenvolvimento Cient{\'i}fico e Tecnol{\'o}gico, Coordena{\c c}{\~a}o de Aperfei{\c c}oamento de Pessoal de N{\'i}vel Superior, and Instituto Nacional de Neuroci{\^e}ncia Translacional. 1. Devinsky O, Ryvlin P, Friedman D. Preventing sudden unexpected death in epilepsy. JAMA Neurol. 2018;75(5):531-532. doi:10.1001/jamaneurol.2018.0400 2. Watkins L, Shankar R, Sander JW. Identifying and mitigating Sudden Unexpected Death in Epilepsy (SUDEP) risk factors. Expert Rev Neurother. 2018;18(4):265-274. doi:10.1080/14737175.2018.1439738 3. Scorza FA, Cysneiros RM, Arida RM, Terra-Bustamante VC, de Albuquerque M, Cavalheiro EA. The other side of the coin: beneficiary effect of omega-3 fatty acids in sudden unexpected death in epilepsy. Epilepsy Behav. 2008;13(2):279-283. doi:10.1016/j.yebeh.2008.04.011",

year = "2018",

month = sep,

doi = "10.1001/jamaneurol.2018.2251",

language = "English (US)",

volume = "75",

pages = "1155",

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T1 - Orthostatic hypotension as a prodromal marker of α-synucleinopathies-Reply

AU - Savica, Rodolfo

AU - Boeve, Bradley F.

AU - Mielke, Michelle M.

N1 - Funding Information: Author Affiliations: Department of Neurology, Dysautonomia Center, New York University School of Medicine, New York. Corresponding Author: Horacio Kaufmann, MD, Department of Neurology, Dysautonomia Center, New York University School of Medicine, 530 First Ave, Ste 9Q, New York, NY 10016 (horacio.kaufmann@nyumc.org). Published Online: August 13, 2018. doi:10.1001/jamaneurol.2018.2248 Conflict of Interest Disclosures: The authors receive funding from National Institutes of Health grant U54NS065736. 1. Savica R, Boeve BF, Mielke MM. When do α-synucleinopathies start? an epidemiological timeline: a review. JAMA Neurol. 2018;75(4):503-509. doi:10.1001/jamaneurol.2017.4243 2. Kaufmann H, Norcliffe-Kaufmann L, Palma JA, et al; Autonomic Disorders Consortium. Natural history of pure autonomic failure: a United States prospective cohort. Ann Neurol. 2017;81(2):287-297. doi:10.1002/ana.24877 3. Postuma RB, Gagnon JF, Pelletier A, Montplaisir J. Prodromal autonomic symptoms and signs in Parkinson’s disease and dementia with Lewy bodies. Mov Disord. 2013;28(5):597-604. doi:10.1002/mds.25445 4. Schrag A, Horsfall L, Walters K, Noyce A, Petersen I. Prediagnostic presentations of Parkinson’s disease in primary care: a case-control study. Lancet Neurol. 2015;14(1):57-64. doi:10.1016/S1474-4422(14)70287-X 5. Berg D, Postuma RB, Adler CH, et al. MDS research criteria for prodromal Parkinson’s disease. Mov Disord. 2015;30(12):1600-1611. doi:10.1002/mds.26431 Funding Information: Conflict of Interest Disclosures: Our research is supported by grants from Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, and Instituto Nacional de Neurociência Translacional. 1. Devinsky O, Ryvlin P, Friedman D. Preventing sudden unexpected death in epilepsy. JAMA Neurol. 2018;75(5):531-532. doi:10.1001/jamaneurol.2018.0400 2. Watkins L, Shankar R, Sander JW. Identifying and mitigating Sudden Unexpected Death in Epilepsy (SUDEP) risk factors. Expert Rev Neurother. 2018;18(4):265-274. doi:10.1080/14737175.2018.1439738 3. Scorza FA, Cysneiros RM, Arida RM, Terra-Bustamante VC, de Albuquerque M, Cavalheiro EA. The other side of the coin: beneficiary effect of omega-3 fatty acids in sudden unexpected death in epilepsy. Epilepsy Behav. 2008;13(2):279-283. doi:10.1016/j.yebeh.2008.04.011

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