Organ transplant recipients and critical care seizures

Deena Nasr, Sara Hocker, Eelco F.M. Wijdicks

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Seizures are an unusual and unexpected post-transplant complication but may have multiple potential etiologies including systemic and central nervous system infections, ischemic infarctions, malignancy, metabolic disturbances, and antirejection medication neurotoxicity. Some of these etiologies are more or less unique to the transplant population and must be reversed in order to prevent recurrent seizures. As with any patient, the first course of action is to confirm there has been a seizure by either a compelling history or EEG recording. A single seizure may result in aspiration and other unwanted medical complications and a short course of treatment with levetiracetam is advised. If there has been new major structural brain injury, seizures may become recurrent or refractory despite abortive therapies. The significance, evaluation, and treatment of seizures in the transplant population are reviewed in this chapter.

Original languageEnglish (US)
Title of host publicationCurrent Clinical Neurology
PublisherHumana Press Inc.
Pages259-268
Number of pages10
Edition9783319495552
DOIs
StatePublished - Jan 1 2017

Publication series

NameCurrent Clinical Neurology
Number9783319495552
ISSN (Print)1559-0585

Keywords

  • Neurologic complications
  • Organ transplant
  • Seizure
  • Stem cell transplant

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Organ transplant recipients and critical care seizures'. Together they form a unique fingerprint.

  • Cite this

    Nasr, D., Hocker, S., & Wijdicks, E. F. M. (2017). Organ transplant recipients and critical care seizures. In Current Clinical Neurology (9783319495552 ed., pp. 259-268). (Current Clinical Neurology; No. 9783319495552). Humana Press Inc.. https://doi.org/10.1007/978-3-319-49557-6_15