Optimal ventilator settings in acute lung injury and acute respiratory distress syndrome

M. Yilmaz, O. Gajic

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Despite recent advances in intensive care medicine, acute lung injury and its more severe form, acute respiratory distress syndrome pose major therapeutic problems. While mechanical ventilation is integral to the care of these patients, its adverse consequences including ventilator-induced lung injury are determinants of disease progression and prognosis. Among several important ventilator parameters, the use of low tidal volumes is probably the most important feature of lung-protective mechanical ventilation. Intensivists should be trained to recognize acute lung injury and acute respiratory distress syndrome and encouraged to use low-tidal-volume ventilation in clinical practice. Alternative modes of ventilation such as high-frequency ventilation and prone position should be reserved for selected patients in whom conventional lung-protective ventilation strategies have failed.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalEuropean Journal of Anaesthesiology
Volume25
Issue number2
DOIs
StatePublished - Feb 1 2008

Keywords

  • Critical Care
  • High-frequency Ventilation
  • Respiration Artificial
  • Respiratory Distress Syndrome Adult

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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