Optimal size matching in single lung transplantation

S. J. Park, J. Houck, R. Pifarre, H. Sullivan, E. Garrity, S. Y. Kim, J. Zbilut, A. Montoya

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Background: Single lung transplantation for patients with end-stage obstructive lung disease has been highly effective in providing symptomatic relief, and it has been performed at a much increased frequency since 1983. However, there still lacks a convincing study showing the effect of size match and other preoperative variables in predicting functional outcome of patients after transplantation. Methods: We evaluated 23 single lung transplantations performed for obstructive lung disease over a 34-month period. Multiple physiologic variables and size match criteria were evaluated for their contribution in determining the postoperative forced expiratory volume in 1 second at 3 months after transplantation. Results: The size match ratio that was based on intramammary chest wall circumference was the most useful criterion to adopt, and the optimal donor/recipient size match ratio was 0.89. Furthermore, forced expiratory volume in 1 second at 3 months after transplantation could be predicted with a simple mathematical model that was based on the size match ratio and the recipient's calculated vital capacity of the transplanted hemithorax. Conclusion: This model could be applied in a clinical setting to maximize functional outcome of the recipients undergoing single lung transplantation.

Original languageEnglish (US)
Pages (from-to)671-675
Number of pages5
JournalJournal of Heart and Lung Transplantation
Volume14
Issue number4
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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    Park, S. J., Houck, J., Pifarre, R., Sullivan, H., Garrity, E., Kim, S. Y., Zbilut, J., & Montoya, A. (1995). Optimal size matching in single lung transplantation. Journal of Heart and Lung Transplantation, 14(4), 671-675.