Optimal management of gastric cancer: Results from an international RAND/UCLA expert panel

Natalie Coburn, Rajini Seevaratnam, Lawrence Paszat, Lucy Helyer, Calvin Law, Carol Swallow, Roberta Cardosa, Alyson Mahar, Laercio Gomes Lourenco, Matthew Dixon, Tanios Bekaii-Saab, Ian Chau, Neal Church, Daniel Coit, Christopher H. Crane, Craig Earle, Paul Mansfield, Norman Marcon, Thomas Miner, Sung Hoon NohGeoff Porter, Mitchell C. Posner, Vivek Prachand, Takeshi Sano, Cornelis Van De Velde, Sandra Wong, Robin McLeod

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

OBJECTIVE: Defining processes of care, which are appropriate and necessary for management of gastric cancer (GC), is an important step toward improving outcomes. METHODS: Using a RAND/UCLA Appropriateness Method, an international multidisciplinary expert panel created 22 statements reflecting optimal management. All statements were scored for appropriateness and necessity. RESULTS: The following tenets were scored appropriate and necessary: (1) preoperative staging by computed tomography of abdomen/pelvis; (2) positron-emission tomographic scans not routinely indicated; (3) consideration for adjuvant therapy; (4) further clinical trials; (5) multidisciplinary decision making; (6) sufficient support at hospitals; (7) assessment of 16 or more lymph nodes (LNs); (8) in metastatic disease, surgery only for palliation of major symptoms; (9) surgeons experienced in GC management; (10) and surgeons experienced in both GC management and advanced laparoscopic surgery for laparoscopic resection. The following were scored appropriate, but of indeterminate necessity: (1) diagnostic laparoscopy before treatment; (2) a multidisciplinary approach to linitis plastica; (3) genetic assessment for diffuse GC and family history, or age less than 45 years; (4) endoscopic removal of select T1aN0 lesions; (5) D2 LN dissection in curative intent cases; (6) D1 LN dissection for early GC or patients with comorbidities; (7) frozen section analysis of margins; (8) nonemergent cases performed in a hospital with a volume of more than 15 resections per year; and (9) by a surgeon with more than 6 resection per year. CONCLUSIONS: The expert panel has created 22 statements for the perioperative management of GC patients, to provide guidance to clinicians and improve the care received by patients.

Original languageEnglish (US)
Pages (from-to)102-108
Number of pages7
JournalAnnals of surgery
Volume259
Issue number1
DOIs
StatePublished - Jan 1 2014

Keywords

  • Cancer
  • Gastric
  • Management
  • Stomach

ASJC Scopus subject areas

  • Surgery

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    Coburn, N., Seevaratnam, R., Paszat, L., Helyer, L., Law, C., Swallow, C., Cardosa, R., Mahar, A., Lourenco, L. G., Dixon, M., Bekaii-Saab, T., Chau, I., Church, N., Coit, D., Crane, C. H., Earle, C., Mansfield, P., Marcon, N., Miner, T., ... McLeod, R. (2014). Optimal management of gastric cancer: Results from an international RAND/UCLA expert panel. Annals of surgery, 259(1), 102-108. https://doi.org/10.1097/SLA.0b013e318288dd2b