Optical detection of high-grade dysplasia in Barrett's esophagus

Louis Michel Wong Kee Song, Brian C. Wilson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Optical spectroscopic and imaging techniques offer the potential to accurately identify tissue pathology in real time. These techniques exploit diagnostic molecular and/or structural information contained in light-tissue interactions, such as fluorescence, elastic scattering, and inelastic (Raman) scattering. In conjunction with endoscopy, they have the capacity to enhance lesion detection in premalignant conditions such as Barrett's esophagus. This article highlights the current status and future prospects of optical spectroscopy and imaging in Barrett's esophagus, with emphasis on their diagnostic potential for the detection of high-grade dysplasia and early adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)78-88
Number of pages11
JournalTechniques in Gastrointestinal Endoscopy
Volume7
Issue number2 SPEC. ISS.
DOIs
StatePublished - Apr 2005

Keywords

  • Barrett's esophagus
  • Confocal endoscopy
  • Fluorescence endoscopy
  • Narrow band imaging
  • Optical coherence tomography
  • Spectroscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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