Optical detection of high-grade dysplasia in Barrett's esophagus

Louis Michel Wong Kee Song; Brian C. Wilson

doi:10.1016/j.tgie.2005.02.006

Optical detection of high-grade dysplasia in Barrett's esophagus

Louis Michel Wong Kee Song, Brian C. Wilson

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Optical spectroscopic and imaging techniques offer the potential to accurately identify tissue pathology in real time. These techniques exploit diagnostic molecular and/or structural information contained in light-tissue interactions, such as fluorescence, elastic scattering, and inelastic (Raman) scattering. In conjunction with endoscopy, they have the capacity to enhance lesion detection in premalignant conditions such as Barrett's esophagus. This article highlights the current status and future prospects of optical spectroscopy and imaging in Barrett's esophagus, with emphasis on their diagnostic potential for the detection of high-grade dysplasia and early adenocarcinoma.

Original language	English (US)
Pages (from-to)	78-88
Number of pages	11
Journal	Techniques in Gastrointestinal Endoscopy
Volume	7
Issue number	2 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.tgie.2005.02.006
State	Published - Apr 2005

Keywords

Barrett's esophagus
Confocal endoscopy
Fluorescence endoscopy
Narrow band imaging
Optical coherence tomography
Spectroscopy

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

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title = "Optical detection of high-grade dysplasia in Barrett's esophagus",

abstract = "Optical spectroscopic and imaging techniques offer the potential to accurately identify tissue pathology in real time. These techniques exploit diagnostic molecular and/or structural information contained in light-tissue interactions, such as fluorescence, elastic scattering, and inelastic (Raman) scattering. In conjunction with endoscopy, they have the capacity to enhance lesion detection in premalignant conditions such as Barrett's esophagus. This article highlights the current status and future prospects of optical spectroscopy and imaging in Barrett's esophagus, with emphasis on their diagnostic potential for the detection of high-grade dysplasia and early adenocarcinoma.",

keywords = "Barrett's esophagus, Confocal endoscopy, Fluorescence endoscopy, Narrow band imaging, Optical coherence tomography, Spectroscopy",

author = "{Wong Kee Song}, {Louis Michel} and Wilson, {Brian C.}",

note = "Funding Information: Supported in part by the Mayo Foundation CR-20 Award Funding Information: This work is supported in part by the Mayo Foundation CR-20 Award. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

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language = "English (US)",

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AU - Wilson, Brian C.

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AB - Optical spectroscopic and imaging techniques offer the potential to accurately identify tissue pathology in real time. These techniques exploit diagnostic molecular and/or structural information contained in light-tissue interactions, such as fluorescence, elastic scattering, and inelastic (Raman) scattering. In conjunction with endoscopy, they have the capacity to enhance lesion detection in premalignant conditions such as Barrett's esophagus. This article highlights the current status and future prospects of optical spectroscopy and imaging in Barrett's esophagus, with emphasis on their diagnostic potential for the detection of high-grade dysplasia and early adenocarcinoma.

KW - Barrett's esophagus

KW - Confocal endoscopy

KW - Fluorescence endoscopy

KW - Narrow band imaging

KW - Optical coherence tomography

KW - Spectroscopy

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Optical detection of high-grade dysplasia in Barrett's esophagus

Abstract

Keywords

ASJC Scopus subject areas

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