Opioid usage after left ventricular assist device implantation: A single center retrospective analysis

Sarah Schettle, Youssef Shahin, Shannon Dunlay, Richard C Daly, Amy Glasgow, Elizabeth Habermann, John Stulak, Andrew Rosenbaum

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Opioid use disorder is a known national concern and extends across multiple populations; however, opioid use in the left ventricular assist device (LVAD) population and subsequent outcomes is not well described. Objectives: We sought to understand opioid use and patient characteristics among the LVAD population at a single center and associated outcomes after index LVAD hospitalization in relation to opioid use. Methods: A single center retrospective review of pre-operative and post-operative opioid use was characterized during the index admission for LVAD implantation. Additionally, we reviewed medical records from patients with opioid prescription at hospital discharge stratified by oral morphine equivalents (OME) and refills of opioid prescriptions with analysis of the outcomes of readmission and death after hospital discharge from the index admission for LVAD implantation. Results: Opioid exposed patients in this cohort increased in frequency from 0% of patients in 2007 to a peak of 25.9% of patients in 2013, and gradually declined thereafter to 12.5% in 2017. Conclusions: Despite the rate of high dose opioid therapy in this cohort, neither opioid use, opioid history, oral morphine equivalents (OME), or opioid refills portended worse survival after LVAD implantation.

Original languageEnglish (US)
Pages (from-to)82-87
Number of pages6
JournalHeart and Lung
Volume59
DOIs
StatePublished - May 1 2023

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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