On Combination of Hadamard-encoded Multi-pulses and Multiplane Wave Transmission in Contrast-Enhanced Ultrasound Imaging

Ping Gong, Pengfei Song, Chengwu Huang, Shigao D Chen

Research output: Contribution to journalArticle

1 Scopus citations


Contrast-enhanced ultrasound (CEUS) imaging has great potential for use in many new ultrasound clinical applications. We recently proposed a novel CEUS imaging sequence, Hadamard-encoded multi-pulses (HEM), to improve the signal-to-noise (SNR) and contrast-to-tissue ratio (CTR) as compared to other classic CEUS methods. HEM increases microbubble responses by using longer coded transmit pulses and the fast polarity change between coded pulses. In this study, we propose to combine the HEM pulse with multiplane wave (MW) imaging technique to further improve CEUS imaging SNR and CNR. During MW-HEM transmissions, the microbubbles undergo multiple fast pulse polarity changes, leading to significantly improved microbubble nonlinear responses, and thus further enhanced SNR and CTR as compared to HEM alone or other CEUS sequences. This improvement may facilitate more robust CEUS imaging for deep abdominal organs and the heart.

Original languageEnglish (US)
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
StateAccepted/In press - Jul 10 2018



  • Band-pass filters
  • Contrast-Enhanced Ultrasound Imaging (CEUS)
  • Decoding
  • Hadamard-encoding
  • Image resolution
  • Imaging
  • Multiplane wave transmission
  • Signal to noise ratio
  • Standards
  • Ultrasonic imaging

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering

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