Olfactory function in parkinson's disease subtypes

M. B. Stern, R. L. Doty, M. Dotti, P. Corcoran, D. Crawford, D. A. Mc Keown, C. Adler, S. Gollomp, H. Hurtig

Research output: Contribution to journalArticle

128 Scopus citations

Abstract

Decreased olfactory function commonly occurs in idiopathic Parkinson's disease (PD), regardless of stage, treatment, or duration of disease. In the present study, we sought to determine whether different subtypes of PD, categorized according to well-defined clinical criteria, evidence different degrees of olfactory dysfunction. Significantly different scores on the University of Pennsylvania Smell Identification Test (UPSIT) were present between patients with benign PD and malignant PD (respective means [SD] = 22.51 [8.50] and 17.38 [6.29]) and between tremor-predominant PD and postural instability-gait disorder (PIGD)-predominant PD (23.43 [8.18] versus 17.35 [6.00]). No statistically significant differences in UPSIT scores were observed between young-onset and older-onset PD patients. Women outperformed men in most subtypes examined.

Original languageEnglish (US)
Pages (from-to)266-268
Number of pages3
JournalNeurology
Volume44
Issue number2
DOIs
StatePublished - Feb 1994

ASJC Scopus subject areas

  • Clinical Neurology

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    Stern, M. B., Doty, R. L., Dotti, M., Corcoran, P., Crawford, D., Mc Keown, D. A., Adler, C., Gollomp, S., & Hurtig, H. (1994). Olfactory function in parkinson's disease subtypes. Neurology, 44(2), 266-268. https://doi.org/10.1212/wnl.44.2.266