Abstract
Purpose: This qualitative study sought to learn patients’ perspectives on olaparib — including maintenance olaparib — in their own words. Methods: Olaparib-treated patients were interviewed by phone. A semi-structured interview guide that focused on symptoms and quality of life was formulated in alignment with the study objective. Interviews were transcribed and analyzed with content analysis. Results: Twenty olaparib-treated patients were interviewed. Four themes emerged: (1) The Long Cancer Journey. Patients prescribed olaparib appear to have had a long cancer journey, sometimes with prior cancer (“I had breast cancer in 1996”) and sometimes with a long interval from an ovarian cancer diagnosis; (2) Adherence. Despite this journey, patients were adherent to olaparib (“I set it for an alarm 15 min before I have to take [olaparib] and then exactly when I’m supposed to take it”); (3) Adherence Despite Challenges. Adherence continued despite side effects (although olaparib was “pretty tolerable”). This adherence also continued despite cost (“…for a month’s supply, mine was $15,837… and my insurance covered some of it but not near enough”), and (4) Modifications in Perceptions of BRCA Status. Olaparib as cancer therapy influenced perceptions of BRCA mutations (“But I… I have to tell you, I’m grateful that I qualified to be on Lynparza®”). Conclusion: Although oral maintenance therapy for ovarian cancer is relatively new, patients appear willing to take olaparib long term; and they seem to take great lengths to remain adherent, despite having sometimes had a long cancer journey.
Original language | English (US) |
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Pages (from-to) | 4807-4812 |
Number of pages | 6 |
Journal | Supportive Care in Cancer |
Volume | 30 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2022 |
Keywords
- Maintenance therapy
- Mutations
- Olaparib
- Ovarian cancer
ASJC Scopus subject areas
- Oncology