Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Eduardo Nunes Chini

doi:10.1016/j.cmet.2020.05.013

Of Mice and Men: NAD⁺ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Eduardo Nunes Chini

Anesthesiology

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD⁺ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD⁺ precursor niacin, identifying NAD⁺ boosting as a potential treatment for this devastating disease.

Original language	English (US)
Pages (from-to)	1041-1043
Number of pages	3
Journal	Cell Metabolism
Volume	31
Issue number	6
DOIs	https://doi.org/10.1016/j.cmet.2020.05.013
State	Published - Jun 2 2020

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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title = "Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients",

abstract = "In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease.",

author = "Chini, {Eduardo Nunes}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

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N2 - In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease.

AB - In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease.

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JO - Cell Metabolism

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Of Mice and Men: NAD⁺ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Abstract

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