TY - JOUR
T1 - Ocular perfusion pressure and pulsatile ocular blood flow in normal and systemic hypertensive patients
AU - Kanadani, Fabio N.
AU - Figueiredo, Carlos R.
AU - Miranda, Rafaela Morais
AU - Cunha, Patricia L.T.
AU - Kanadani, Tereza Cristina M.
AU - Dorairaj, Syril
N1 - Publisher Copyright:
© 2015, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Purpose: Glaucomatous neuropathy can be a consequence of insufficient blood supply, increase in intraocular pressure (IOP), or other risk factors that diminish the ocular blood flow. To determine the ocular perfusion pressure (OPP) in normal and systemic hypertensive patients. Materials and methods: One hundred and twenty-one patients were enrolled in this prospective and comparative study and underwent a complete ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, stereoscopic fundus examination, and pulsatile ocular blood flow (POBF) measurements. The OPP was calculated as being the medium systemic arterial pressure (MAP) less the IOP. Only right eye values were considered for calculations using Student’s t-test. Results: The mean age of the patients was 57.5 years (36-78), and 68.5% were women. There was a statistically significant difference in the OPP of the normal and systemic hypertensive patients (p < 0.05). The difference in the OPP between these groups varied between 8.84 and 17.9 mm Hg. Conclusion: The results of this study suggest that although the systemic hypertensive patients have a higher OPP in comparison to normal patients, this increase does not mean that they also have a higher OBF (as measured by POBF tonograph). This may be caused by chronic changes in the vascular network and in the blood hemodynamics in patients with systemic hypertension.
AB - Purpose: Glaucomatous neuropathy can be a consequence of insufficient blood supply, increase in intraocular pressure (IOP), or other risk factors that diminish the ocular blood flow. To determine the ocular perfusion pressure (OPP) in normal and systemic hypertensive patients. Materials and methods: One hundred and twenty-one patients were enrolled in this prospective and comparative study and underwent a complete ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, stereoscopic fundus examination, and pulsatile ocular blood flow (POBF) measurements. The OPP was calculated as being the medium systemic arterial pressure (MAP) less the IOP. Only right eye values were considered for calculations using Student’s t-test. Results: The mean age of the patients was 57.5 years (36-78), and 68.5% were women. There was a statistically significant difference in the OPP of the normal and systemic hypertensive patients (p < 0.05). The difference in the OPP between these groups varied between 8.84 and 17.9 mm Hg. Conclusion: The results of this study suggest that although the systemic hypertensive patients have a higher OPP in comparison to normal patients, this increase does not mean that they also have a higher OBF (as measured by POBF tonograph). This may be caused by chronic changes in the vascular network and in the blood hemodynamics in patients with systemic hypertension.
KW - Glaucoma
KW - Ocular perfusion pressure
KW - Pulsatile ocular blood flow
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U2 - 10.5005/jp-journals-10008-1177
DO - 10.5005/jp-journals-10008-1177
M3 - Article
AN - SCOPUS:85046705408
SN - 0974-0333
VL - 9
SP - 16
EP - 19
JO - Journal of Current Glaucoma Practice
JF - Journal of Current Glaucoma Practice
IS - 1
ER -