Purpose. To investigate the long-term follow-up of ocular colobomas in pediatric patients with particular attention to the prevalence of retinal detachment. Methods. The authors reviewed the charts of 42 consecutive patients with colobomas followed in two academic pediatric eye clinics. Results. Seventy-six affected eyes of 42 patients were identified, involvement ranged from iris colobomas to large colobomas affecting the optic nerve, choroid, and retina. Mean age at initial exam was 27 months with an average follow-up of 6 years 5 months. Mean age at last visit was 8 years 8 months. Refractive error ranged from -14 to +18. Twelve eyes were microphthalmic and six had microcornea. Fourteen patients (33%) had other developmental abnormalities. Four retinal detachments (5%) were found, three between the ages of 5 and 29 months and the fourth occurred after minor head trauma at age 10. One choroidal detachment was found at age 9 years 4 months. Conclusion. Thirty-three percent of patients with ocular colobomas have other systemic findings. In addition, pediatric patients with ocular colobomas had a 5% prevalence of retinal detachment in this series. These occurred in patients with large colobomas that invovled the optic nerve head and inferior retina, and occurred at very young ages with little or no known trauma. Surgical repair is difficult with limited results in this setting. Early ophthalmic evaluation with follow-up is important. Prophylactic laser demarcation may be indicated in patients with large colobomas.
|Original language||English (US)|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Feb 15 1996|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience