Ocular colobomas and long-term follow-up in a pediatric population

D. R. Daufenbach, Jose S Pulido, M. S. Ruttum, R. V. Keech

Research output: Contribution to journalArticle

Abstract

Purpose. To investigate the long-term follow-up of ocular colobomas in pediatric patients with particular attention to the prevalence of retinal detachment. Methods. The authors reviewed the charts of 42 consecutive patients with colobomas followed in two academic pediatric eye clinics. Results. Seventy-six affected eyes of 42 patients were identified, involvement ranged from iris colobomas to large colobomas affecting the optic nerve, choroid, and retina. Mean age at initial exam was 27 months with an average follow-up of 6 years 5 months. Mean age at last visit was 8 years 8 months. Refractive error ranged from -14 to +18. Twelve eyes were microphthalmic and six had microcornea. Fourteen patients (33%) had other developmental abnormalities. Four retinal detachments (5%) were found, three between the ages of 5 and 29 months and the fourth occurred after minor head trauma at age 10. One choroidal detachment was found at age 9 years 4 months. Conclusion. Thirty-three percent of patients with ocular colobomas have other systemic findings. In addition, pediatric patients with ocular colobomas had a 5% prevalence of retinal detachment in this series. These occurred in patients with large colobomas that invovled the optic nerve head and inferior retina, and occurred at very young ages with little or no known trauma. Surgical repair is difficult with limited results in this setting. Early ophthalmic evaluation with follow-up is important. Prophylactic laser demarcation may be indicated in patients with large colobomas.

Original languageEnglish (US)
JournalInvestigative Ophthalmology and Visual Science
Volume37
Issue number3
StatePublished - Feb 15 1996
Externally publishedYes

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Coloboma
Pediatrics
Population
Retinal Detachment
Retina
Refractive Errors
Choroid
Optic Disk
Iris
Craniocerebral Trauma
Lasers
Wounds and Injuries

ASJC Scopus subject areas

  • Ophthalmology

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Ocular colobomas and long-term follow-up in a pediatric population. / Daufenbach, D. R.; Pulido, Jose S; Ruttum, M. S.; Keech, R. V.

In: Investigative Ophthalmology and Visual Science, Vol. 37, No. 3, 15.02.1996.

Research output: Contribution to journalArticle

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abstract = "Purpose. To investigate the long-term follow-up of ocular colobomas in pediatric patients with particular attention to the prevalence of retinal detachment. Methods. The authors reviewed the charts of 42 consecutive patients with colobomas followed in two academic pediatric eye clinics. Results. Seventy-six affected eyes of 42 patients were identified, involvement ranged from iris colobomas to large colobomas affecting the optic nerve, choroid, and retina. Mean age at initial exam was 27 months with an average follow-up of 6 years 5 months. Mean age at last visit was 8 years 8 months. Refractive error ranged from -14 to +18. Twelve eyes were microphthalmic and six had microcornea. Fourteen patients (33{\%}) had other developmental abnormalities. Four retinal detachments (5{\%}) were found, three between the ages of 5 and 29 months and the fourth occurred after minor head trauma at age 10. One choroidal detachment was found at age 9 years 4 months. Conclusion. Thirty-three percent of patients with ocular colobomas have other systemic findings. In addition, pediatric patients with ocular colobomas had a 5{\%} prevalence of retinal detachment in this series. These occurred in patients with large colobomas that invovled the optic nerve head and inferior retina, and occurred at very young ages with little or no known trauma. Surgical repair is difficult with limited results in this setting. Early ophthalmic evaluation with follow-up is important. Prophylactic laser demarcation may be indicated in patients with large colobomas.",
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