Occupation, education, and Parkinson's disease: A case-control study in an Italian population

Walter A. Rocca, Dallas W. Anderson, Francesca Meneghini, Francesco Grigoletto, Letterio Morgante, Arturo Reggio, Giovanni Savettieri, Raoul Di Perri

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Current epidemiologic data on the association between occupational exposures and Parkinson's disease (PD) are inconsistent. In a case-control study, we investigated the associations between occupation and PD and between education and PD. The cases (n = 62) were those identified in a prevalence survey (door-to-door, two-phase) of three Sicilian municipalities, as of November 1, 1987. We then randomly selected from the general population two controls for each case, matched for age (±1 year), sex, and municipality (n = 124). Information on current and past occupations and education for cases and controls was obtained during the survey. Subjects who worked for most of their lives as farmers were not at increased risk of PD (OR = 0.6; 95% CI = 0.3-1.3). Neither were subjects who worked for most of their lives in other occupations (e.g., housewives, fishermen, factory workers, salesmen, craftsmen, clerks). PD was not associated with low education. Our findings suggest that farming, as a broad occupational category, does not play a major role in the causation of PD.

Original languageEnglish (US)
Pages (from-to)201-206
Number of pages6
JournalMovement Disorders
Volume11
Issue number2
DOIs
StatePublished - Jan 1 1996

Keywords

  • Case-control studies
  • Education
  • Occupation
  • Parkinson's disease
  • Risk factors

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    Rocca, W. A., Anderson, D. W., Meneghini, F., Grigoletto, F., Morgante, L., Reggio, A., Savettieri, G., & Di Perri, R. (1996). Occupation, education, and Parkinson's disease: A case-control study in an Italian population. Movement Disorders, 11(2), 201-206. https://doi.org/10.1002/mds.870110214