Obstructive sleep apnea as a cause of neurogenic hypertension

Krzysztof Narkiewicz, Virend Somers

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Abnormalities in neural circulatory control may contribute importantly to the hypertensive state. The sympathetic nervous system in particular is a key mechanism for increasing blood pressure. Patients with obstructive sleep apnea have increased sympathetic activity. Obesity or other coexisting disease states do not explain the heightened sympathetic drive. This review examines the evidence linking sleep apnea with hypertension and the possible role of excessive sympathetic drive as a mediator of higher blood pressure in sleep apnea. Abnormalities in reflex circulatory control that could act to increase sympathetic activity in sleep apnea are also discussed.

Original languageEnglish (US)
Pages (from-to)268-273
Number of pages6
JournalCurrent Hypertension Reports
Volume1
Issue number3
DOIs
StatePublished - 1999
Externally publishedYes

Fingerprint

Sleep Apnea Syndromes
Obstructive Sleep Apnea
Hypertension
Sympathetic Nervous System
Reflex
Obesity
Blood Pressure
Drive

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Obstructive sleep apnea as a cause of neurogenic hypertension. / Narkiewicz, Krzysztof; Somers, Virend.

In: Current Hypertension Reports, Vol. 1, No. 3, 1999, p. 268-273.

Research output: Contribution to journalArticle

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