TY - JOUR
T1 - Obstructive sleep apnea and hypertension
AU - Narkiewicz, Krzysztof
AU - Wolf, Jacek
AU - Lopez-Jimenez, Francisco
AU - Somers, Virend K.
PY - 2005/11
Y1 - 2005/11
N2 - There is growing evidence of a causal relationship between obstructive sleep apnea (OSA) and hypertension. Untreated OSA may have direct and deleterious effects on cardiovascular function and structure through several mechanisms, including sympathetic activation, oxidative stress, inflammation, and endothelial dysfunction. OSA may contribute to or augment elevated blood pressure levels in a large proportion of the hypertensive patient population. It is important to consider OSA in the differential diagnosis of hypertensive patients who are obese. OSA should be especially considered in those hypertensive patients who respond poorly to combination therapy with antihypertensive medications.
AB - There is growing evidence of a causal relationship between obstructive sleep apnea (OSA) and hypertension. Untreated OSA may have direct and deleterious effects on cardiovascular function and structure through several mechanisms, including sympathetic activation, oxidative stress, inflammation, and endothelial dysfunction. OSA may contribute to or augment elevated blood pressure levels in a large proportion of the hypertensive patient population. It is important to consider OSA in the differential diagnosis of hypertensive patients who are obese. OSA should be especially considered in those hypertensive patients who respond poorly to combination therapy with antihypertensive medications.
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U2 - 10.1007/s11886-005-0061-z
DO - 10.1007/s11886-005-0061-z
M3 - Review article
C2 - 16256012
AN - SCOPUS:28244449025
SN - 1523-3782
VL - 7
SP - 435
EP - 440
JO - Current cardiology reports
JF - Current cardiology reports
IS - 6
ER -