Obese patients undergoing cystectomy: A population-based, propensity score matched analysis

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To examine the impact of body mass index, as a measure of obesity, on the surgical outcomes of cystectomy. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was used to acquire data on 1293 cystectomies carried out from 2005 to 2011. Patients were divided into two groups: body mass index <30kg/m2 and ≥30kg/m2. A propensity score-matched analysis of perioperative outcomes was carried out. Results: A total of 869 patients had a body mass index <30, whereas 424 had a body mass index ≥30. Unadjusted comparisons showed higher rates of superficial surgical site infections (8.7% vs 5.3%, P=0.04), renal insufficiency (4.0% vs 1.7%, P=0.01) and increased operative times (365.7min vs 338.6min, P=0.0004) in the obese patients, but interestingly lower rates of pneumonia (2.4% vs 4.8, P=0.03) and cerebral vascular accidents (0.0% vs 0.9%, P=0.05). However, the latter two observations might be explained by more tobacco use among non-obese patients (26.6mean pack-years vs 20.0mean pack-years, P=0.004). Notably, no differences in 30-day mortality were noted. After adjusting for preoperative demographic and clinical data using propensity score-matching methods, there were no observed differences between the two cohorts except for operative time (P=0.04). Conclusions: Obesity is not independently associated with an increased risk of perioperative complications or 30-day mortality after cystectomy.

Original languageEnglish (US)
Pages (from-to)491-495
Number of pages5
JournalInternational Journal of Urology
Volume21
Issue number5
DOIs
StatePublished - 2014

Fingerprint

Propensity Score
Cystectomy
Body Mass Index
Operative Time
Population
Obesity
Surgical Wound Infection
Mortality
Tobacco Use
Quality Improvement
Accidents
Renal Insufficiency
Blood Vessels
Pneumonia
Demography
Databases

Keywords

  • Cystectomy
  • Mortality
  • Obesity
  • Propensity score
  • Surgical outcomes

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

Cite this

Obese patients undergoing cystectomy : A population-based, propensity score matched analysis. / Tyson, Mark D.; Humphreys, Mitchell R; Castle, Erik P.

In: International Journal of Urology, Vol. 21, No. 5, 2014, p. 491-495.

Research output: Contribution to journalArticle

@article{cfa4320efc994dea9fc42c115d993b6b,
title = "Obese patients undergoing cystectomy: A population-based, propensity score matched analysis",
abstract = "Objective: To examine the impact of body mass index, as a measure of obesity, on the surgical outcomes of cystectomy. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was used to acquire data on 1293 cystectomies carried out from 2005 to 2011. Patients were divided into two groups: body mass index <30kg/m2 and ≥30kg/m2. A propensity score-matched analysis of perioperative outcomes was carried out. Results: A total of 869 patients had a body mass index <30, whereas 424 had a body mass index ≥30. Unadjusted comparisons showed higher rates of superficial surgical site infections (8.7{\%} vs 5.3{\%}, P=0.04), renal insufficiency (4.0{\%} vs 1.7{\%}, P=0.01) and increased operative times (365.7min vs 338.6min, P=0.0004) in the obese patients, but interestingly lower rates of pneumonia (2.4{\%} vs 4.8, P=0.03) and cerebral vascular accidents (0.0{\%} vs 0.9{\%}, P=0.05). However, the latter two observations might be explained by more tobacco use among non-obese patients (26.6mean pack-years vs 20.0mean pack-years, P=0.004). Notably, no differences in 30-day mortality were noted. After adjusting for preoperative demographic and clinical data using propensity score-matching methods, there were no observed differences between the two cohorts except for operative time (P=0.04). Conclusions: Obesity is not independently associated with an increased risk of perioperative complications or 30-day mortality after cystectomy.",
keywords = "Cystectomy, Mortality, Obesity, Propensity score, Surgical outcomes",
author = "Tyson, {Mark D.} and Humphreys, {Mitchell R} and Castle, {Erik P}",
year = "2014",
doi = "10.1111/iju.12340",
language = "English (US)",
volume = "21",
pages = "491--495",
journal = "International Journal of Urology",
issn = "0919-8172",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Obese patients undergoing cystectomy

T2 - A population-based, propensity score matched analysis

AU - Tyson, Mark D.

AU - Humphreys, Mitchell R

AU - Castle, Erik P

PY - 2014

Y1 - 2014

N2 - Objective: To examine the impact of body mass index, as a measure of obesity, on the surgical outcomes of cystectomy. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was used to acquire data on 1293 cystectomies carried out from 2005 to 2011. Patients were divided into two groups: body mass index <30kg/m2 and ≥30kg/m2. A propensity score-matched analysis of perioperative outcomes was carried out. Results: A total of 869 patients had a body mass index <30, whereas 424 had a body mass index ≥30. Unadjusted comparisons showed higher rates of superficial surgical site infections (8.7% vs 5.3%, P=0.04), renal insufficiency (4.0% vs 1.7%, P=0.01) and increased operative times (365.7min vs 338.6min, P=0.0004) in the obese patients, but interestingly lower rates of pneumonia (2.4% vs 4.8, P=0.03) and cerebral vascular accidents (0.0% vs 0.9%, P=0.05). However, the latter two observations might be explained by more tobacco use among non-obese patients (26.6mean pack-years vs 20.0mean pack-years, P=0.004). Notably, no differences in 30-day mortality were noted. After adjusting for preoperative demographic and clinical data using propensity score-matching methods, there were no observed differences between the two cohorts except for operative time (P=0.04). Conclusions: Obesity is not independently associated with an increased risk of perioperative complications or 30-day mortality after cystectomy.

AB - Objective: To examine the impact of body mass index, as a measure of obesity, on the surgical outcomes of cystectomy. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was used to acquire data on 1293 cystectomies carried out from 2005 to 2011. Patients were divided into two groups: body mass index <30kg/m2 and ≥30kg/m2. A propensity score-matched analysis of perioperative outcomes was carried out. Results: A total of 869 patients had a body mass index <30, whereas 424 had a body mass index ≥30. Unadjusted comparisons showed higher rates of superficial surgical site infections (8.7% vs 5.3%, P=0.04), renal insufficiency (4.0% vs 1.7%, P=0.01) and increased operative times (365.7min vs 338.6min, P=0.0004) in the obese patients, but interestingly lower rates of pneumonia (2.4% vs 4.8, P=0.03) and cerebral vascular accidents (0.0% vs 0.9%, P=0.05). However, the latter two observations might be explained by more tobacco use among non-obese patients (26.6mean pack-years vs 20.0mean pack-years, P=0.004). Notably, no differences in 30-day mortality were noted. After adjusting for preoperative demographic and clinical data using propensity score-matching methods, there were no observed differences between the two cohorts except for operative time (P=0.04). Conclusions: Obesity is not independently associated with an increased risk of perioperative complications or 30-day mortality after cystectomy.

KW - Cystectomy

KW - Mortality

KW - Obesity

KW - Propensity score

KW - Surgical outcomes

UR - http://www.scopus.com/inward/record.url?scp=84899472195&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899472195&partnerID=8YFLogxK

U2 - 10.1111/iju.12340

DO - 10.1111/iju.12340

M3 - Article

C2 - 24256162

AN - SCOPUS:84899472195

VL - 21

SP - 491

EP - 495

JO - International Journal of Urology

JF - International Journal of Urology

SN - 0919-8172

IS - 5

ER -