Nutritional Deficiencies in Celiac Disease

Susan H. Barton, Darlene G. Kelly, Joseph A. Murray

Research output: Contribution to journalReview article

40 Scopus citations

Abstract

Celiac disease is characterized by small bowel enteropathy, precipitated in genetically susceptible individuals by the ingestion of "gluten," which is a term used to encompass the storage proteins of wheat, rye, and barley. Although the intestine heals with removal of gluten from the diet, the intolerance is permanent and the damage recurs if gluten is reintroduced. This damage causes a wide variety of consequence including maldigestion and malabsorption, resulting in the characteristic, although not universal, features of malnutrition. This article examines recent advances in the understanding of the spectrum of celiac disease, illustrates the impact of celiac disease on nutrition, and describes approaches to the management of the disease.

Original languageEnglish (US)
Pages (from-to)93-108
Number of pages16
JournalGastroenterology Clinics of North America
Volume36
Issue number1
DOIs
StatePublished - Mar 1 2007

ASJC Scopus subject areas

  • Gastroenterology

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