Nutrient partitioning

Samyah Shadid, Michael Dennis Jensen

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Nutrient partitioning can be defined as the process by which the organism selects fuels for storage (including protein synthesis) or oxidation. Understanding the regulation of energy balance and nutrient partitioning can potentially facilitate the treatment of obesity. Although the factors that lead to an imbalance between energy/fat intake and energy expenditure, and thus the development of obesity, remain incompletely understood, nutrient partitioning may be especially relevant to the development of obesity as it relates to the hypothesis of Flatt (1). The latter suggests that total food intake increases to meet carbohydrate needs. According to this theory, food intake is regulated, at least in part, to assure an adequate amount of carbohydrate. Consumption of a high-fat diet would require the intake of excess fat in order to satisfy carbohydrate needs and therefore lead to obesity under this scenario. The concept of a diet “relatively” deficient in carbohydrate becomes important in that dysregulation of substrate partitioning could potentially affect the body's sense of what constitutes adequate carbohydrate intake. For example, if fat were preferentially shunted toward storage, more carbohydrate would be required to meet oxidative needs, thereby preventing suffcient repletion of glycogen stores. This process is proposed to generate signals that stimulate appetite. Other examples where nutrient partitioning relates to obesity and body fat content include the stimulation of lean tissue synthesis at the expense of fat calories by androgens and growth hormone, and (presumably) the reverse of this process by deficiencies of these hormones.

Original languageEnglish (US)
Title of host publicationHandbook of Obesity
Subtitle of host publicationEtiology and Pathophysiology, Second Edition
PublisherCRC Press
Pages753-766
Number of pages14
ISBN (Electronic)9780203913376
ISBN (Print)9780824709693
StatePublished - Jan 1 2003

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Carbohydrates
Obesity
Food
Fats
Eating
High Fat Diet
Appetite
Energy Intake
Glycogen
Energy Metabolism
Androgens
Growth Hormone
Adipose Tissue
Hormones
Diet
Proteins
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Shadid, S., & Jensen, M. D. (2003). Nutrient partitioning. In Handbook of Obesity: Etiology and Pathophysiology, Second Edition (pp. 753-766). CRC Press.

Nutrient partitioning. / Shadid, Samyah; Jensen, Michael Dennis.

Handbook of Obesity: Etiology and Pathophysiology, Second Edition. CRC Press, 2003. p. 753-766.

Research output: Chapter in Book/Report/Conference proceedingChapter

Shadid, S & Jensen, MD 2003, Nutrient partitioning. in Handbook of Obesity: Etiology and Pathophysiology, Second Edition. CRC Press, pp. 753-766.
Shadid S, Jensen MD. Nutrient partitioning. In Handbook of Obesity: Etiology and Pathophysiology, Second Edition. CRC Press. 2003. p. 753-766
Shadid, Samyah ; Jensen, Michael Dennis. / Nutrient partitioning. Handbook of Obesity: Etiology and Pathophysiology, Second Edition. CRC Press, 2003. pp. 753-766
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