Nutcracker phenomenon and nutcracker syndrome

Andrew K. Kurklinsky, Thom W Rooke

Research output: Contribution to journalReview article

182 Citations (Scopus)

Abstract

Nutcracker phenomenon refers to compression of the left renal vein, most commonly between the aorta and the superior mesenteric artery, with impaired blood outflow often accompanied by distention of the distal portion of the vein. The nutcracker syndrome (NCS) is the clinical equivalent of nutcracker phenomenon characterized by a complex of symptoms with substantial variations. Depending on specific manifestations, NCS may be encountered by different medical specialists. Although it may be associated with substantial morbidity, the diagnosis of NCS is often difficult and is commonly delayed. Diagnostic and treatment criteria are not well established, and the natural history of NCS is not well understood. We performed an initial review of the literature through MEDLINE, searching from 1950 to date and using the keywords nutcracker syndrome, nutcracker phenomenon, and renal vein entrapment. We performed additional reviews based on the literature citations of the identified articles. We attempted to elucidate clinical relevance of these conditions and their prominent features and to summarize professional experience.

Original languageEnglish (US)
Pages (from-to)552-559
Number of pages8
JournalMayo Clinic Proceedings
Volume85
Issue number6
DOIs
StatePublished - 2010

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Renal Veins
Superior Mesenteric Artery
Natural History
MEDLINE
Aorta
Veins
Morbidity
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nutcracker phenomenon and nutcracker syndrome. / Kurklinsky, Andrew K.; Rooke, Thom W.

In: Mayo Clinic Proceedings, Vol. 85, No. 6, 2010, p. 552-559.

Research output: Contribution to journalReview article

Kurklinsky, Andrew K. ; Rooke, Thom W. / Nutcracker phenomenon and nutcracker syndrome. In: Mayo Clinic Proceedings. 2010 ; Vol. 85, No. 6. pp. 552-559.
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