TY - JOUR
T1 - Novel Nonsurgical Endoscopic Approaches for the Treatment of Obesity
AU - Hurt, Ryan T.
AU - Frazier, Thomas H.
AU - Mundi, Manpreet S.
N1 - Publisher Copyright:
© 2017 The American Society for Parenteral and Enteral Nutrition.
PY - 2017/8/1
Y1 - 2017/8/1
N2 - Globally, obesity is a leading cause of preventable death and is associated with >60 comorbid medical conditions, including 10 types of cancer that are strongly associated with body mass index. There are a number of traditional obesity treatments - for example, lifestyle management (eg, decreased caloric intake and increased expenditure), pharmacotherapy, and bariatric surgery. Recently, endoscopic approaches have emerged as a viable alternative for weight loss. Endoscopically placed intragastric balloons were introduced in the early 1980s for the treatment of medically complicated obesity but, unfortunately, had high rates of complications, such as premature deflation leading to obstruction. Despite these shortcomings, these devices have experienced a renewal, with a second generation of improved devices being approved for clinical use in 2015. In addition to the intragastric balloons, there are a number of other endoscopic approaches to weight loss that are either Food and Drug Administration approved or undergoing evaluation (aspiration therapy, duodenal jejunal bypass sleeve). The current review examines the literature available and discusses the practical clinical considerations involved.
AB - Globally, obesity is a leading cause of preventable death and is associated with >60 comorbid medical conditions, including 10 types of cancer that are strongly associated with body mass index. There are a number of traditional obesity treatments - for example, lifestyle management (eg, decreased caloric intake and increased expenditure), pharmacotherapy, and bariatric surgery. Recently, endoscopic approaches have emerged as a viable alternative for weight loss. Endoscopically placed intragastric balloons were introduced in the early 1980s for the treatment of medically complicated obesity but, unfortunately, had high rates of complications, such as premature deflation leading to obstruction. Despite these shortcomings, these devices have experienced a renewal, with a second generation of improved devices being approved for clinical use in 2015. In addition to the intragastric balloons, there are a number of other endoscopic approaches to weight loss that are either Food and Drug Administration approved or undergoing evaluation (aspiration therapy, duodenal jejunal bypass sleeve). The current review examines the literature available and discusses the practical clinical considerations involved.
KW - bariatric surgery
KW - endoscopy; weight loss
KW - gastric balloon
KW - obesity
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U2 - 10.1177/0884533617714235
DO - 10.1177/0884533617714235
M3 - Review article
C2 - 28622478
AN - SCOPUS:85026746064
SN - 0884-5336
VL - 32
SP - 493
EP - 501
JO - Nutrition in Clinical Practice
JF - Nutrition in Clinical Practice
IS - 4
ER -