Novel applications of modified ultrafiltration and autologous priming techniques to reduce blood product exposure on ECMO

James R. Neal, Caitlin L. Blau, Amanda M. Cornelius, Roxann B. Pike, Joseph A. Dearani, Bassem N. Mora

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Patients needing the assistance of extracorporeal membrane oxygenation (ECMO) are at risk of hemodilution and, in some instances, may require exposure to large amounts of allogeneic blood products. Patient outcomes can be improved by taking steps to reduce transfusions and hemodilution. Currently, modified ultrafiltration (MUF) is used across the world to reduce hemodilution after cardiopulmonary bypass (CPB). Another common technique during bypass initiation is autologous priming. By applying modified versions of these techniques, ECMO patients may potentially benefit. Usually, patients requiring immediate transition from CPB to ECMO are not stable enough to tolerate MUF. Through alterations of the CPB and ECMO circuit tubing, MUF can be performed once on ECMO. Another technique to potentially lower the transfusion requirements for ECMO patients is a complete circuit blood transfer during an ECMO circuit exchange. While selective component changes are preferred if possible, occasionally a complete circuit change must be done. To minimize hemodilution or prevent priming with blood products, the original ECMO circuit's blood can be transferred to the new ECMO circuit before connecting to the patient. Both of these techniques, in our opinion, helped to reduce the number of transfusions that our ECMO patients have seen during these critical time periods.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalJournal of Extra-Corporeal Technology
Volume48
Issue number1
StatePublished - 2016

Fingerprint

Extracorporeal Membrane Oxygenation
Ultrafiltration
Hemodilution
Cardiopulmonary Bypass

Keywords

  • Autologous priming
  • Blood conservation
  • Extracorporeal membrane oxygenation
  • Modified ultrafiltration

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Neal, J. R., Blau, C. L., Cornelius, A. M., Pike, R. B., Dearani, J. A., & Mora, B. N. (2016). Novel applications of modified ultrafiltration and autologous priming techniques to reduce blood product exposure on ECMO. Journal of Extra-Corporeal Technology, 48(1), 23-26.

Novel applications of modified ultrafiltration and autologous priming techniques to reduce blood product exposure on ECMO. / Neal, James R.; Blau, Caitlin L.; Cornelius, Amanda M.; Pike, Roxann B.; Dearani, Joseph A.; Mora, Bassem N.

In: Journal of Extra-Corporeal Technology, Vol. 48, No. 1, 2016, p. 23-26.

Research output: Contribution to journalArticle

Neal, JR, Blau, CL, Cornelius, AM, Pike, RB, Dearani, JA & Mora, BN 2016, 'Novel applications of modified ultrafiltration and autologous priming techniques to reduce blood product exposure on ECMO', Journal of Extra-Corporeal Technology, vol. 48, no. 1, pp. 23-26.
Neal, James R. ; Blau, Caitlin L. ; Cornelius, Amanda M. ; Pike, Roxann B. ; Dearani, Joseph A. ; Mora, Bassem N. / Novel applications of modified ultrafiltration and autologous priming techniques to reduce blood product exposure on ECMO. In: Journal of Extra-Corporeal Technology. 2016 ; Vol. 48, No. 1. pp. 23-26.
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