Nosocomial Pneumococcal Bacteremia

Salvador Alvarez, Juan Guarderas, Charles G. Shell, Shirley Holtsclaw Berk, Steven L. Berk

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

• In five years we studied 56 episodes of pneumococcal bacteremia. Twenty-three (41%) were nosocomial and 33 (59%) community acquired. Most of our patients were elderly men with multiple underlying diseases; however, those patients with nosocomial infections had a significantly higher incidence of malignant neoplasms (57% vs 24%), poor functional status (70% vs 25%), and ultimately fatal underlying disease (61% vs 21%). Alcoholism was more common among the patients with community-acquired bacteremia (45% vs 17%). Nosocomial infections carried a significantly higher overall mortality (73.9% vs 45.4%). The mortality directly related to the pneumococcal bacteremia was also higher (52% vs 39%), but not significantly. Most of the isolated strains were serotypes present in the new pneumococcal vaccine, which only one study patient had received. Mixed pneumococcal bacteremia with gram-negative bacilli was more frequent in nosocomial infections. Streptococcus pneumoniae can be a nosocomial pathogen in elderly, debilitated patients. Pneumococcal vaccination should be incorporated in a hospital-based prevention program for high-risk patients.

Original languageEnglish (US)
Pages (from-to)1509-1512
Number of pages4
JournalArchives of Internal Medicine
Volume146
Issue number8
DOIs
StatePublished - 1986
Externally publishedYes

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Bacteremia
Cross Infection
Pneumococcal Vaccines
Mortality
Streptococcus pneumoniae
Bacillus
Alcoholism
Vaccination
Incidence
Neoplasms

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Alvarez, S., Guarderas, J., Shell, C. G., Holtsclaw Berk, S., & Berk, S. L. (1986). Nosocomial Pneumococcal Bacteremia. Archives of Internal Medicine, 146(8), 1509-1512. https://doi.org/10.1001/archinte.1986.00360200059010

Nosocomial Pneumococcal Bacteremia. / Alvarez, Salvador; Guarderas, Juan; Shell, Charles G.; Holtsclaw Berk, Shirley; Berk, Steven L.

In: Archives of Internal Medicine, Vol. 146, No. 8, 1986, p. 1509-1512.

Research output: Contribution to journalArticle

Alvarez, S, Guarderas, J, Shell, CG, Holtsclaw Berk, S & Berk, SL 1986, 'Nosocomial Pneumococcal Bacteremia', Archives of Internal Medicine, vol. 146, no. 8, pp. 1509-1512. https://doi.org/10.1001/archinte.1986.00360200059010
Alvarez S, Guarderas J, Shell CG, Holtsclaw Berk S, Berk SL. Nosocomial Pneumococcal Bacteremia. Archives of Internal Medicine. 1986;146(8):1509-1512. https://doi.org/10.1001/archinte.1986.00360200059010
Alvarez, Salvador ; Guarderas, Juan ; Shell, Charles G. ; Holtsclaw Berk, Shirley ; Berk, Steven L. / Nosocomial Pneumococcal Bacteremia. In: Archives of Internal Medicine. 1986 ; Vol. 146, No. 8. pp. 1509-1512.
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