Normal-pressure hydrocephalus. Onset of gait abnormality before dementia predicts good surgical outcome

Neill R Graff Radford, J. C. Godersky

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

In 1977, Fisher reported that in patients with possible normal-pressure hydrocephalus (NPH), if the gait abnormality preceded dementia, surgery usually had a favorable outcome and vice versa. We studied this finding in 21 patients shunted for possible NPH. By evaluating serial videotapes of gait, neuropsychological tests, and Katz index ratings, preoperatively and at approximately two months and six months postoperatively, we judged 16 patients improved. In the improved group, the families reported that the gait abnormality preceded the dementia in 11 patients and occurred at the same time in five. In the unimproved group, dementia was noted first in three patients, gait abnormality first in one patient, and gait abnormality and dementia at the same time in one patient. Using Fisher's exact test, we compared the improved and unimproved groups for gait abnormality or dementia onset first and found a significant difference. We conclude that the history of gait abnormality occurring before or after dementia in patients with possible NPH is an important prognostic factor for surgical outcome.

Original languageEnglish (US)
Pages (from-to)940-942
Number of pages3
JournalArchives of Neurology
Volume43
Issue number9
StatePublished - 1986
Externally publishedYes

Fingerprint

Normal Pressure Hydrocephalus
Gait
Dementia
Videotape Recording
Onset
Hydrocephalus
Neuropsychological Tests
History

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Normal-pressure hydrocephalus. Onset of gait abnormality before dementia predicts good surgical outcome. / Graff Radford, Neill R; Godersky, J. C.

In: Archives of Neurology, Vol. 43, No. 9, 1986, p. 940-942.

Research output: Contribution to journalArticle

@article{39848f5053b649d1a8e0d61c90217748,
title = "Normal-pressure hydrocephalus. Onset of gait abnormality before dementia predicts good surgical outcome",
abstract = "In 1977, Fisher reported that in patients with possible normal-pressure hydrocephalus (NPH), if the gait abnormality preceded dementia, surgery usually had a favorable outcome and vice versa. We studied this finding in 21 patients shunted for possible NPH. By evaluating serial videotapes of gait, neuropsychological tests, and Katz index ratings, preoperatively and at approximately two months and six months postoperatively, we judged 16 patients improved. In the improved group, the families reported that the gait abnormality preceded the dementia in 11 patients and occurred at the same time in five. In the unimproved group, dementia was noted first in three patients, gait abnormality first in one patient, and gait abnormality and dementia at the same time in one patient. Using Fisher's exact test, we compared the improved and unimproved groups for gait abnormality or dementia onset first and found a significant difference. We conclude that the history of gait abnormality occurring before or after dementia in patients with possible NPH is an important prognostic factor for surgical outcome.",
author = "{Graff Radford}, {Neill R} and Godersky, {J. C.}",
year = "1986",
language = "English (US)",
volume = "43",
pages = "940--942",
journal = "Archives of Neurology",
issn = "0003-9942",
publisher = "American Medical Association",
number = "9",

}

TY - JOUR

T1 - Normal-pressure hydrocephalus. Onset of gait abnormality before dementia predicts good surgical outcome

AU - Graff Radford, Neill R

AU - Godersky, J. C.

PY - 1986

Y1 - 1986

N2 - In 1977, Fisher reported that in patients with possible normal-pressure hydrocephalus (NPH), if the gait abnormality preceded dementia, surgery usually had a favorable outcome and vice versa. We studied this finding in 21 patients shunted for possible NPH. By evaluating serial videotapes of gait, neuropsychological tests, and Katz index ratings, preoperatively and at approximately two months and six months postoperatively, we judged 16 patients improved. In the improved group, the families reported that the gait abnormality preceded the dementia in 11 patients and occurred at the same time in five. In the unimproved group, dementia was noted first in three patients, gait abnormality first in one patient, and gait abnormality and dementia at the same time in one patient. Using Fisher's exact test, we compared the improved and unimproved groups for gait abnormality or dementia onset first and found a significant difference. We conclude that the history of gait abnormality occurring before or after dementia in patients with possible NPH is an important prognostic factor for surgical outcome.

AB - In 1977, Fisher reported that in patients with possible normal-pressure hydrocephalus (NPH), if the gait abnormality preceded dementia, surgery usually had a favorable outcome and vice versa. We studied this finding in 21 patients shunted for possible NPH. By evaluating serial videotapes of gait, neuropsychological tests, and Katz index ratings, preoperatively and at approximately two months and six months postoperatively, we judged 16 patients improved. In the improved group, the families reported that the gait abnormality preceded the dementia in 11 patients and occurred at the same time in five. In the unimproved group, dementia was noted first in three patients, gait abnormality first in one patient, and gait abnormality and dementia at the same time in one patient. Using Fisher's exact test, we compared the improved and unimproved groups for gait abnormality or dementia onset first and found a significant difference. We conclude that the history of gait abnormality occurring before or after dementia in patients with possible NPH is an important prognostic factor for surgical outcome.

UR - http://www.scopus.com/inward/record.url?scp=0022462193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022462193&partnerID=8YFLogxK

M3 - Article

VL - 43

SP - 940

EP - 942

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 9

ER -