Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM): A reversible form of encephalopathy

Richard John Caselli, Bradley F Boeve, B. W. Scheithauer, J. D. O'Duffy, G. G. Hunder

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Five patients, age 54 to 80 years, presented between 3 weeks and 18 months after symptomatic onset of progressive cognitive decline, psychosis, and unsteady gait that proved to be due to a steroid-responsive nonvasculitic autoimmune inflammatory meningoencephalitic syndrome. CSF examination showed elevated immunoglobulin (Ig)G index and IgG synthesis rate in all three patients in whom it was checked, and brain biopsy revealed perivascular lymphocytic infiltrates without vessel wall invasion.

Original languageEnglish (US)
Pages (from-to)1579-1581
Number of pages3
JournalNeurology
Volume53
Issue number7
StatePublished - Oct 22 1999

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Meningoencephalitis
Brain Diseases
Immunoglobulin G
Neurologic Gait Disorders
Psychotic Disorders
Steroids
Biopsy
Brain
Cognitive Dysfunction

Keywords

  • Autoimmunity
  • Dementia
  • Encephalopathy
  • Meningoencephalitis
  • Sjogren's syndrome

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) : A reversible form of encephalopathy. / Caselli, Richard John; Boeve, Bradley F; Scheithauer, B. W.; O'Duffy, J. D.; Hunder, G. G.

In: Neurology, Vol. 53, No. 7, 22.10.1999, p. 1579-1581.

Research output: Contribution to journalArticle

Caselli, Richard John ; Boeve, Bradley F ; Scheithauer, B. W. ; O'Duffy, J. D. ; Hunder, G. G. / Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) : A reversible form of encephalopathy. In: Neurology. 1999 ; Vol. 53, No. 7. pp. 1579-1581.
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