TY - JOUR
T1 - Nontuberculous mycobacterial (NTM) lung disease
T2 - The top ten essentials
AU - Aksamit, Timothy R.
AU - Philley, Julie V.
AU - Griffith, David E.
PY - 2014/3
Y1 - 2014/3
N2 - This review will utilize essential questions about nontuberculous mycobacterial (NTM) lung disease to succinctly address important new developments in the pathogenesis, diagnosis and management of NTM lung disease with a focus on practical information and "bottom line" answers. What do I tell my patients who ask, "where did I get this infection" and, "should I take showers"?What is the connection between bronchiectasis and the acquisition of NTM lung infection?What other factors are important in the pathogenesis of NTM lung disease?Why does it seem that am I seeing more new NTM lung disease patients?Why is the diagnosis of NTM lung disease so complicated and does the diagnosis of NTM lung infection obligate specific treatment?Unlike traditional tuberculosis, what is behind the irrelevance of most in vitro susceptibility testing reports for NTM infections?Is there anything new for the management of patients with Mycobacterium avium complex lung disease? How does the radiographic appearance influence treatment?Is there anything new for the management of patients with Mycobacterium abscessus lung disease?What about the management of other NTM respiratory pathogens?Is there a role for the use of macrolide monotherapy for non-cystic fibrosis bronchiectasis?
AB - This review will utilize essential questions about nontuberculous mycobacterial (NTM) lung disease to succinctly address important new developments in the pathogenesis, diagnosis and management of NTM lung disease with a focus on practical information and "bottom line" answers. What do I tell my patients who ask, "where did I get this infection" and, "should I take showers"?What is the connection between bronchiectasis and the acquisition of NTM lung infection?What other factors are important in the pathogenesis of NTM lung disease?Why does it seem that am I seeing more new NTM lung disease patients?Why is the diagnosis of NTM lung disease so complicated and does the diagnosis of NTM lung infection obligate specific treatment?Unlike traditional tuberculosis, what is behind the irrelevance of most in vitro susceptibility testing reports for NTM infections?Is there anything new for the management of patients with Mycobacterium avium complex lung disease? How does the radiographic appearance influence treatment?Is there anything new for the management of patients with Mycobacterium abscessus lung disease?What about the management of other NTM respiratory pathogens?Is there a role for the use of macrolide monotherapy for non-cystic fibrosis bronchiectasis?
KW - Mycobacterium abscessus
KW - Mycobacterium avium Complex (MAC)
KW - Nontuberculous mycobacteria
UR - http://www.scopus.com/inward/record.url?scp=84896697001&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84896697001&partnerID=8YFLogxK
U2 - 10.1016/j.rmed.2013.09.014
DO - 10.1016/j.rmed.2013.09.014
M3 - Review article
C2 - 24484653
AN - SCOPUS:84896697001
SN - 0954-6111
VL - 108
SP - 417
EP - 425
JO - British Journal of Tuberculosis and Diseases of the Chest
JF - British Journal of Tuberculosis and Diseases of the Chest
IS - 3
ER -