Abstract
Angiogenesis plays an important role in the pathophysiology of atherosclerosis and after myocardial infarction. Furthermore, angiogenesis has been the focus of many therapeutic strategies. In view of that, a direct and clear understanding of the role of these pathways in the living subject is needed. Molecular imaging has emerged as a powerful tool to study biological processes noninvasively. This review presents and discusses evidence on the feasibility of different molecular imaging strategies to study the involvement of angiogenic pathways in the assessment of the atherosclerotic disease and as a tool to assess angiogenic therapy. Focus is placed on imaging modalities with the potential to be translated to clinical use.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 59-66 |
| Number of pages | 8 |
| Journal | Current Cardiovascular Imaging Reports |
| Volume | 2 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2009 |
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ASJC Scopus subject areas
- Cell Biology
- Histology
- Applied Microbiology and Biotechnology
Cite this
Noninvasive monitoring of myocardial angiogenesis. / Rodriguez-Porcel, Martin G.
In: Current Cardiovascular Imaging Reports, Vol. 2, No. 1, 2009, p. 59-66.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Noninvasive monitoring of myocardial angiogenesis
AU - Rodriguez-Porcel, Martin G
PY - 2009
Y1 - 2009
N2 - Angiogenesis plays an important role in the pathophysiology of atherosclerosis and after myocardial infarction. Furthermore, angiogenesis has been the focus of many therapeutic strategies. In view of that, a direct and clear understanding of the role of these pathways in the living subject is needed. Molecular imaging has emerged as a powerful tool to study biological processes noninvasively. This review presents and discusses evidence on the feasibility of different molecular imaging strategies to study the involvement of angiogenic pathways in the assessment of the atherosclerotic disease and as a tool to assess angiogenic therapy. Focus is placed on imaging modalities with the potential to be translated to clinical use.
AB - Angiogenesis plays an important role in the pathophysiology of atherosclerosis and after myocardial infarction. Furthermore, angiogenesis has been the focus of many therapeutic strategies. In view of that, a direct and clear understanding of the role of these pathways in the living subject is needed. Molecular imaging has emerged as a powerful tool to study biological processes noninvasively. This review presents and discusses evidence on the feasibility of different molecular imaging strategies to study the involvement of angiogenic pathways in the assessment of the atherosclerotic disease and as a tool to assess angiogenic therapy. Focus is placed on imaging modalities with the potential to be translated to clinical use.
UR - http://www.scopus.com/inward/record.url?scp=84859634966&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859634966&partnerID=8YFLogxK
U2 - 10.1007/s12410-009-0008-7
DO - 10.1007/s12410-009-0008-7
M3 - Review article
AN - SCOPUS:84859634966
VL - 2
SP - 59
EP - 66
JO - Current Cardiovascular Imaging Reports
JF - Current Cardiovascular Imaging Reports
SN - 1941-9066
IS - 1
ER -