Abstract
Background Systemic vascular resistance (SVR) is an integral therapeutic component of patients with heart failure and shock. We hypothesized that the ratio of the peak mitral regurgitant velocity (MRV) (m/s) to left ventricular outflow time-velocity integral (TVILVOT) (cm) by Doppler would provide a noninvasive correlate of SVR. Methods SVR was correlated to MRV/TVILVOT in 33 patients undergoing right heart catheterization. Receiver operating characteristic curves were generated to determine the best-balanced sensitivity and specificity to identify SVR > 14 Wood units (WU) and <10 WU. Results MRV/TVILVOT correlated well with SVR (r = 0.842, 95% confidence interval 0.7-0.92, P < .001, Y = 0.459 + 49.397*X). By receiver operating characteristics, MRV/TVILVOT > 0.27 had a 70% sensitivity and a 77% specificity to identify SVR > 14 WU. MRV/TVILVOT < 0.2 had a 92% sensitivity and a 88% specificity to identify SVR < 10 WU. Conclusion Doppler echocardiography provides a reliable noninvasive assessment of SVR.
Original language | English (US) |
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Pages (from-to) | 834-838 |
Number of pages | 5 |
Journal | Journal of the American Society of Echocardiography |
Volume | 17 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2004 |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine