Noninvasive coronary artery angiography using electron beam computed tomography

John A. Rumberger, Benno J. Rensing, Judd E. Reed, Erik L M D Ritman, Patrick F M D Sheedy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Electron beam computed tomography (EBCT), also known as ultrafast-CT or cine-CT, uses a unique scanning architecture which allows for multiple high spatial resolution electrocardiographic triggered images of the beating heart. A recent study has demonstrated the feasibility of qualitative comparisons between EBCT derived 3D coronary angiograms and invasive angiography. Stenoses of the proximal portions of the left anterior descending and right coronary arteries were readily identified, but description of atherosclerotic narrowing in the left circumflex artery (and distal epicardial disease) was not possible with any degree of confidence. Although these preliminary studies support the notion that this approach has potential, the images overall were suboptimal for clinical application as an adjunct to invasive angiography. Furthermore, these studies did not examine different methods of EBCT scan acquisition, tomographic slice thicknesses, extent of scan overlap, or other segmentation, thresholding, and interpolation algorithms. Our laboratory has initiated investigation of these aspects and limitations of EBCT coronary angiography. Specific areas of research include defining effects of cardiac orientation; defining the effects of tomographic slice thickness and intensity (gradient) versus positional (shaped based) interpolation; and defining applicability of imaging each of the major epicardial coronary arteries for quantitative definition of vessel size, cross-sectional area, taper, and discrete vessel narrowing.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsEric A. Hoffman
Pages93-106
Number of pages14
Volume2709
StatePublished - 1996
EventMedical Imaging 1996: Physiology and Function from Multidimensional Images - Newport Beach, CA, USA
Duration: Feb 11 1996Feb 13 1996

Other

OtherMedical Imaging 1996: Physiology and Function from Multidimensional Images
CityNewport Beach, CA, USA
Period2/11/962/13/96

Fingerprint

Electron beam computed tomography
Angiography
angiography
arteries
tomography
electron beams
vessels
interpolation
Interpolation
tapering
confidence
acquisition
spatial resolution
Scanning
Imaging techniques
gradients
scanning
high resolution

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Rumberger, J. A., Rensing, B. J., Reed, J. E., Ritman, E. L. M. D., & Sheedy, P. F. M. D. (1996). Noninvasive coronary artery angiography using electron beam computed tomography. In E. A. Hoffman (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2709, pp. 93-106)

Noninvasive coronary artery angiography using electron beam computed tomography. / Rumberger, John A.; Rensing, Benno J.; Reed, Judd E.; Ritman, Erik L M D; Sheedy, Patrick F M D.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Eric A. Hoffman. Vol. 2709 1996. p. 93-106.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rumberger, JA, Rensing, BJ, Reed, JE, Ritman, ELMD & Sheedy, PFMD 1996, Noninvasive coronary artery angiography using electron beam computed tomography. in EA Hoffman (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2709, pp. 93-106, Medical Imaging 1996: Physiology and Function from Multidimensional Images, Newport Beach, CA, USA, 2/11/96.
Rumberger JA, Rensing BJ, Reed JE, Ritman ELMD, Sheedy PFMD. Noninvasive coronary artery angiography using electron beam computed tomography. In Hoffman EA, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2709. 1996. p. 93-106
Rumberger, John A. ; Rensing, Benno J. ; Reed, Judd E. ; Ritman, Erik L M D ; Sheedy, Patrick F M D. / Noninvasive coronary artery angiography using electron beam computed tomography. Proceedings of SPIE - The International Society for Optical Engineering. editor / Eric A. Hoffman. Vol. 2709 1996. pp. 93-106
@inproceedings{6783a5100ebf48099776cbf30f0bd572,
title = "Noninvasive coronary artery angiography using electron beam computed tomography",
abstract = "Electron beam computed tomography (EBCT), also known as ultrafast-CT or cine-CT, uses a unique scanning architecture which allows for multiple high spatial resolution electrocardiographic triggered images of the beating heart. A recent study has demonstrated the feasibility of qualitative comparisons between EBCT derived 3D coronary angiograms and invasive angiography. Stenoses of the proximal portions of the left anterior descending and right coronary arteries were readily identified, but description of atherosclerotic narrowing in the left circumflex artery (and distal epicardial disease) was not possible with any degree of confidence. Although these preliminary studies support the notion that this approach has potential, the images overall were suboptimal for clinical application as an adjunct to invasive angiography. Furthermore, these studies did not examine different methods of EBCT scan acquisition, tomographic slice thicknesses, extent of scan overlap, or other segmentation, thresholding, and interpolation algorithms. Our laboratory has initiated investigation of these aspects and limitations of EBCT coronary angiography. Specific areas of research include defining effects of cardiac orientation; defining the effects of tomographic slice thickness and intensity (gradient) versus positional (shaped based) interpolation; and defining applicability of imaging each of the major epicardial coronary arteries for quantitative definition of vessel size, cross-sectional area, taper, and discrete vessel narrowing.",
author = "Rumberger, {John A.} and Rensing, {Benno J.} and Reed, {Judd E.} and Ritman, {Erik L M D} and Sheedy, {Patrick F M D}",
year = "1996",
language = "English (US)",
isbn = "0819420840",
volume = "2709",
pages = "93--106",
editor = "Hoffman, {Eric A.}",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - Noninvasive coronary artery angiography using electron beam computed tomography

AU - Rumberger, John A.

AU - Rensing, Benno J.

AU - Reed, Judd E.

AU - Ritman, Erik L M D

AU - Sheedy, Patrick F M D

PY - 1996

Y1 - 1996

N2 - Electron beam computed tomography (EBCT), also known as ultrafast-CT or cine-CT, uses a unique scanning architecture which allows for multiple high spatial resolution electrocardiographic triggered images of the beating heart. A recent study has demonstrated the feasibility of qualitative comparisons between EBCT derived 3D coronary angiograms and invasive angiography. Stenoses of the proximal portions of the left anterior descending and right coronary arteries were readily identified, but description of atherosclerotic narrowing in the left circumflex artery (and distal epicardial disease) was not possible with any degree of confidence. Although these preliminary studies support the notion that this approach has potential, the images overall were suboptimal for clinical application as an adjunct to invasive angiography. Furthermore, these studies did not examine different methods of EBCT scan acquisition, tomographic slice thicknesses, extent of scan overlap, or other segmentation, thresholding, and interpolation algorithms. Our laboratory has initiated investigation of these aspects and limitations of EBCT coronary angiography. Specific areas of research include defining effects of cardiac orientation; defining the effects of tomographic slice thickness and intensity (gradient) versus positional (shaped based) interpolation; and defining applicability of imaging each of the major epicardial coronary arteries for quantitative definition of vessel size, cross-sectional area, taper, and discrete vessel narrowing.

AB - Electron beam computed tomography (EBCT), also known as ultrafast-CT or cine-CT, uses a unique scanning architecture which allows for multiple high spatial resolution electrocardiographic triggered images of the beating heart. A recent study has demonstrated the feasibility of qualitative comparisons between EBCT derived 3D coronary angiograms and invasive angiography. Stenoses of the proximal portions of the left anterior descending and right coronary arteries were readily identified, but description of atherosclerotic narrowing in the left circumflex artery (and distal epicardial disease) was not possible with any degree of confidence. Although these preliminary studies support the notion that this approach has potential, the images overall were suboptimal for clinical application as an adjunct to invasive angiography. Furthermore, these studies did not examine different methods of EBCT scan acquisition, tomographic slice thicknesses, extent of scan overlap, or other segmentation, thresholding, and interpolation algorithms. Our laboratory has initiated investigation of these aspects and limitations of EBCT coronary angiography. Specific areas of research include defining effects of cardiac orientation; defining the effects of tomographic slice thickness and intensity (gradient) versus positional (shaped based) interpolation; and defining applicability of imaging each of the major epicardial coronary arteries for quantitative definition of vessel size, cross-sectional area, taper, and discrete vessel narrowing.

UR - http://www.scopus.com/inward/record.url?scp=0029724951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029724951&partnerID=8YFLogxK

M3 - Conference contribution

SN - 0819420840

SN - 9780819420848

VL - 2709

SP - 93

EP - 106

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Hoffman, Eric A.

ER -