Nondiagnostic thyroid fine-needle aspiration biopsies are no longer a dilemma

Melanie L. Richards, Elizabeth Bohnenblust, Kenneth Sirinek, Juliane Bingener

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background: Nondiagnostic fine-needle aspiration biopsy (ND-FNAB) of the thyroid leads to unnecessary thyroidectomy. The aims of this study were as follows: (1) to determine the risk of malignancy in ND-FNABs, and (2) to evaluate factors that may identify patients at risk for a ND-FNAB. Methods: A total of 241 patients who underwent FNAB and thyroidectomy were evaluated for factors associated with a ND-FNAB. Results: A total of 215 women and 26 men underwent FNAB and thyroidectomy. ND-FNAs occurred in 51 of 241 (21%) patients. Ultrasound guidance did not reduce the likelihood of a ND biopsy. Patients with nodules greater than 3 cm had more ND-FNAs. Twenty-one of 51 with a ND biopsy underwent a repeat FNAB. Repeat FNAB was ND in 29% of patients. There was malignant disease in 7 of 51 (14%) with a ND-FNAB. Patient age, sex, thyroid function, gland size, multiple nodules, and final pathology were not related to a ND-FNAB (P > .05). Conclusions: Most patients with a ND-FNAB have benign disease and low-risk patients with a ND-FNAB on repeat FNA warrant a more conservative approach.

Original languageEnglish (US)
Pages (from-to)398-402
Number of pages5
JournalAmerican Journal of Surgery
Volume196
Issue number3
DOIs
StatePublished - Sep 2008
Externally publishedYes

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Fine Needle Biopsy
Thyroid Gland
Thyroidectomy
Biopsy
Pathology
Neoplasms

Keywords

  • Fine-needle aspiration
  • Nondiagnostic
  • Thyroid

ASJC Scopus subject areas

  • Surgery

Cite this

Nondiagnostic thyroid fine-needle aspiration biopsies are no longer a dilemma. / Richards, Melanie L.; Bohnenblust, Elizabeth; Sirinek, Kenneth; Bingener, Juliane.

In: American Journal of Surgery, Vol. 196, No. 3, 09.2008, p. 398-402.

Research output: Contribution to journalArticle

Richards, Melanie L. ; Bohnenblust, Elizabeth ; Sirinek, Kenneth ; Bingener, Juliane. / Nondiagnostic thyroid fine-needle aspiration biopsies are no longer a dilemma. In: American Journal of Surgery. 2008 ; Vol. 196, No. 3. pp. 398-402.
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