Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations

Nikola Reinhard Dürr, Waleed Brinjikji, Anne Pohrt, Henrich Lanfermann, Friedhelm Brassel, Dan Meila

Research output: Contribution to journalArticle

Abstract

Background and purpose Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. Materials and methods We retrospectively evaluated a consecutive series of VGM patients who underwent a 1.5 T MRI protocol, including standard T2 weighted images (T2WI), arterial time of flight (TOF), and thin T2WI without flow compensation (T2OffPh). The primary outcome was the proportion of patients in whom VGM subtypes and all arterial feeders (anterior (AChA) and posterior (PChA) choroidal arteries, pericallosal arteries, basilar tip, and leptomeningeal supply) could be accurately identified compared with a DSA gold standard. Results A total of 26 VGM patients who underwent 108 studies were used in the statistical analysis. VGM subtype was best seen in axial T2OffPh (92.1%) and TOF (89.8%). AChA feeders were best seen in TOF (86.5%) and axial T2OffPh (72.2%). PChA feeders were best seen in TOF (95.1%) and axial T2OffPh (88.1%). Pericallosal feeders were best seen in axial T2OffPh (95.4%) and TOF (95.1%). Basilar tip feeders were best seen in TOF (90.6%) and axial T2OffPh (88.4%). Conclusion VGM angioarchitecture is best seen in TOF and axial T2OffPh. It can be used as an alternative to global angiographic series.

Original languageEnglish (US)
Pages (from-to)999-1004
Number of pages6
JournalJournal of neurointerventional surgery
Volume10
Issue number10
DOIs
StatePublished - Oct 1 2018

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Vein of Galen Malformations
Basilar Artery
Magnetic Resonance Angiography
Arteries

Keywords

  • angiography
  • fistula
  • magnetic resonance angiography
  • mri
  • vascular malformation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations. / Dürr, Nikola Reinhard; Brinjikji, Waleed; Pohrt, Anne; Lanfermann, Henrich; Brassel, Friedhelm; Meila, Dan.

In: Journal of neurointerventional surgery, Vol. 10, No. 10, 01.10.2018, p. 999-1004.

Research output: Contribution to journalArticle

Dürr, Nikola Reinhard ; Brinjikji, Waleed ; Pohrt, Anne ; Lanfermann, Henrich ; Brassel, Friedhelm ; Meila, Dan. / Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations. In: Journal of neurointerventional surgery. 2018 ; Vol. 10, No. 10. pp. 999-1004.
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title = "Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations",
abstract = "Background and purpose Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. Materials and methods We retrospectively evaluated a consecutive series of VGM patients who underwent a 1.5 T MRI protocol, including standard T2 weighted images (T2WI), arterial time of flight (TOF), and thin T2WI without flow compensation (T2OffPh). The primary outcome was the proportion of patients in whom VGM subtypes and all arterial feeders (anterior (AChA) and posterior (PChA) choroidal arteries, pericallosal arteries, basilar tip, and leptomeningeal supply) could be accurately identified compared with a DSA gold standard. Results A total of 26 VGM patients who underwent 108 studies were used in the statistical analysis. VGM subtype was best seen in axial T2OffPh (92.1{\%}) and TOF (89.8{\%}). AChA feeders were best seen in TOF (86.5{\%}) and axial T2OffPh (72.2{\%}). PChA feeders were best seen in TOF (95.1{\%}) and axial T2OffPh (88.1{\%}). Pericallosal feeders were best seen in axial T2OffPh (95.4{\%}) and TOF (95.1{\%}). Basilar tip feeders were best seen in TOF (90.6{\%}) and axial T2OffPh (88.4{\%}). Conclusion VGM angioarchitecture is best seen in TOF and axial T2OffPh. It can be used as an alternative to global angiographic series.",
keywords = "angiography, fistula, magnetic resonance angiography, mri, vascular malformation",
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T1 - Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations

AU - Dürr, Nikola Reinhard

AU - Brinjikji, Waleed

AU - Pohrt, Anne

AU - Lanfermann, Henrich

AU - Brassel, Friedhelm

AU - Meila, Dan

PY - 2018/10/1

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N2 - Background and purpose Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. Materials and methods We retrospectively evaluated a consecutive series of VGM patients who underwent a 1.5 T MRI protocol, including standard T2 weighted images (T2WI), arterial time of flight (TOF), and thin T2WI without flow compensation (T2OffPh). The primary outcome was the proportion of patients in whom VGM subtypes and all arterial feeders (anterior (AChA) and posterior (PChA) choroidal arteries, pericallosal arteries, basilar tip, and leptomeningeal supply) could be accurately identified compared with a DSA gold standard. Results A total of 26 VGM patients who underwent 108 studies were used in the statistical analysis. VGM subtype was best seen in axial T2OffPh (92.1%) and TOF (89.8%). AChA feeders were best seen in TOF (86.5%) and axial T2OffPh (72.2%). PChA feeders were best seen in TOF (95.1%) and axial T2OffPh (88.1%). Pericallosal feeders were best seen in axial T2OffPh (95.4%) and TOF (95.1%). Basilar tip feeders were best seen in TOF (90.6%) and axial T2OffPh (88.4%). Conclusion VGM angioarchitecture is best seen in TOF and axial T2OffPh. It can be used as an alternative to global angiographic series.

AB - Background and purpose Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. Materials and methods We retrospectively evaluated a consecutive series of VGM patients who underwent a 1.5 T MRI protocol, including standard T2 weighted images (T2WI), arterial time of flight (TOF), and thin T2WI without flow compensation (T2OffPh). The primary outcome was the proportion of patients in whom VGM subtypes and all arterial feeders (anterior (AChA) and posterior (PChA) choroidal arteries, pericallosal arteries, basilar tip, and leptomeningeal supply) could be accurately identified compared with a DSA gold standard. Results A total of 26 VGM patients who underwent 108 studies were used in the statistical analysis. VGM subtype was best seen in axial T2OffPh (92.1%) and TOF (89.8%). AChA feeders were best seen in TOF (86.5%) and axial T2OffPh (72.2%). PChA feeders were best seen in TOF (95.1%) and axial T2OffPh (88.1%). Pericallosal feeders were best seen in axial T2OffPh (95.4%) and TOF (95.1%). Basilar tip feeders were best seen in TOF (90.6%) and axial T2OffPh (88.4%). Conclusion VGM angioarchitecture is best seen in TOF and axial T2OffPh. It can be used as an alternative to global angiographic series.

KW - angiography

KW - fistula

KW - magnetic resonance angiography

KW - mri

KW - vascular malformation

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