Multivesicular bodies (MVBs) are critical for a variety of cellular functions ranging from lysosomal degradation to the budding of HIV. To date, delivery into MVBs has been dependent on the ESCRT machinery. However, analysis of a melanosomal protein has uncovered an alternative pathway for MVB sorting.
ASJC Scopus subject areas
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Developmental Biology
- Cell Biology