No ESCRT to the melanosome: MVB sorting without ubiquitin

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

Multivesicular bodies (MVBs) are critical for a variety of cellular functions ranging from lysosomal degradation to the budding of HIV. To date, delivery into MVBs has been dependent on the ESCRT machinery. However, analysis of a melanosomal protein has uncovered an alternative pathway for MVB sorting.

Original languageEnglish (US)
Pages (from-to)278-280
Number of pages3
JournalDevelopmental Cell
Volume10
Issue number3
DOIs
StatePublished - Mar 2006

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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