No differences in manic-like behaviors between voluntary ethanol and water drinking in Lateral Hypothalamic Kindled (LHK) alcohol preferring rats

Noha Abdel Gawad, Khalid Mohamed, Doo Sup Choi, Osama A Abulseoud

Research output: Contribution to journalArticle

Abstract

This study investigates phenotypic differences of manic-like behaviors during voluntary ethanol (vs. water) intake in alcohol preferring (P) rats, using the lateral hypothalamus kindled (LHK) rat mania model. Alcohol preferring (P) rats exhibited classic manic-like behaviors during kindling and the post-kindling intervals in all coded behaviors (p < 0.0001), lending further validity to the lateral hypothalamus kindled rat as a useful model to study mania. However, there was no significant phenotypic difference between alcohol and water drinking alcohol preferring (P) rats.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalPsychiatry Research
Volume261
DOIs
StatePublished - Mar 1 2018

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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